Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2013 1
2019 2
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

4 results

Results by year

Filters applied: . Clear all
Page 1
CHP1 Regulates Compartmentalized Glycerolipid Synthesis by Activating GPAT4.
Zhu XG, Nicholson Puthenveedu S, Shen Y, La K, Ozlu C, Wang T, Klompstra D, Gultekin Y, Chi J, Fidelin J, Peng T, Molina H, Hang HC, Min W, Birsoy K. Zhu XG, et al. Mol Cell. 2019 Apr 4;74(1):45-58.e7. doi: 10.1016/j.molcel.2019.01.037. Epub 2019 Mar 4. Mol Cell. 2019. PMID: 30846317 Free PMC article.
Loss of CHP1 severely reduces fatty acid incorporation and storage in mammalian cells and invertebrates. Mechanistically, CHP1 binds and activates GPAT4, which catalyzes the initial rate-limiting step in glycerolipid synthesis. GPAT4 activity requires CHP1 to be N-m …
Loss of CHP1 severely reduces fatty acid incorporation and storage in mammalian cells and invertebrates. Mechanistically, CHP1 binds and act …
Establishment of a prognostic model for ovarian cancer based on mitochondrial metabolism-related genes.
Meng C, Sun Y, Liu G. Meng C, et al. Front Oncol. 2023 May 15;13:1144430. doi: 10.3389/fonc.2023.1144430. eCollection 2023. Front Oncol. 2023. PMID: 37256178 Free PMC article.
METHODS: First of all, screened differentially expressed genes (DEGs) between TCGA-HGSOC and GTEx-normal by limma, with RNA-seq related HGSOC sourced from The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) database. ...The study structured a MMRGs-rel …
METHODS: First of all, screened differentially expressed genes (DEGs) between TCGA-HGSOC and GTEx-normal by limma, with RNA-seq related HGSO …
Transcriptional Regulation of Acyl-CoA:Glycerol-sn-3-Phosphate Acyltransferases.
Karasawa K, Tanigawa K, Harada A, Yamashita A. Karasawa K, et al. Int J Mol Sci. 2019 Feb 22;20(4):964. doi: 10.3390/ijms20040964. Int J Mol Sci. 2019. PMID: 30813330 Free PMC article. Review.
The enzymes of mammalian species are classified into four isoforms; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane. The activity of each enzyme expressed is associated with phys …
The enzymes of mammalian species are classified into four isoforms; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, where …
Glycerol-3-phosphate acyltransferase (GPAT)-1, but not GPAT4, incorporates newly synthesized fatty acids into triacylglycerol and diminishes fatty acid oxidation.
Wendel AA, Cooper DE, Ilkayeva OR, Muoio DM, Coleman RA. Wendel AA, et al. J Biol Chem. 2013 Sep 20;288(38):27299-27306. doi: 10.1074/jbc.M113.485219. Epub 2013 Aug 1. J Biol Chem. 2013. PMID: 23908354 Free PMC article.
Four glycerol-3-phosphate acyltransferase (GPAT) isoforms, each encoded by a separate gene, catalyze the initial step in glycerolipid synthesis; in liver, the major isoforms are GPAT1 and GPAT4. To determine whether each of these hepatic isoforms performs a unique function …
Four glycerol-3-phosphate acyltransferase (GPAT) isoforms, each encoded by a separate gene, catalyze the initial step in glycerolipid synthe …