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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
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2010 2
2011 3
2012 3
2013 1
2014 1
2015 1
2016 1
2017 2
2019 3
2020 2
2021 5
2022 6
2023 3
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29 results

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Page 1
Gene methylation in gastric cancer.
Qu Y, Dang S, Hou P. Qu Y, et al. Clin Chim Acta. 2013 Sep 23;424:53-65. doi: 10.1016/j.cca.2013.05.002. Epub 2013 May 10. Clin Chim Acta. 2013. PMID: 23669186 Free article. Review.
Gastric cancer is one of the most common malignancies and remains the second leading cause of cancer-related death worldwide. ...Aberrant DNA methylation in the promoter regions of gene, which leads to inactivation of tumor suppressor and other cancer-related …
Gastric cancer is one of the most common malignancies and remains the second leading cause of cancer-related death worldwide. …
GRIK2 is a target for bladder cancer stem-like cell-targeting immunotherapy.
Miyata H, Hirohashi Y, Yamada S, Yanagawa J, Murai A, Hashimoto S, Tokita S, Hori K, Abe T, Kubo T, Tsukahara T, Kanaseki T, Shinohara N, Torigoe T. Miyata H, et al. Cancer Immunol Immunother. 2022 Apr;71(4):795-806. doi: 10.1007/s00262-021-03025-z. Epub 2021 Aug 18. Cancer Immunol Immunother. 2022. PMID: 34405274 Free PMC article.
Recent studies have revealed that treatment-resistant cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) can be targeted by cytotoxic T lymphocytes (CTLs). ...A GRIK2 peptide-specific CTL clone recognized GRIK2-overexpressing UM-UC-3 cells an …
Recent studies have revealed that treatment-resistant cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) can be targ …
Gastric cancer: basic aspects.
Resende C, Thiel A, Machado JC, Ristimäki A. Resende C, et al. Helicobacter. 2011 Sep;16 Suppl 1:38-44. doi: 10.1111/j.1523-5378.2011.00879.x. Helicobacter. 2011. PMID: 21896084 Review.
Gastric cancer (GC) is a world health burden, ranging as the second cause of cancer death worldwide. ...Several genes have been newly associated with gastric carcinogenesis, both through oncogenic activation (GSK3beta, CD133, DSC2, P-Cadherin, CDH17, CD168, CD44, me …
Gastric cancer (GC) is a world health burden, ranging as the second cause of cancer death worldwide. ...Several genes have bee …
GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis.
Inoue R, Hirohashi Y, Kitamura H, Nishida S, Murai A, Takaya A, Yamamoto E, Matsuki M, Tanaka T, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Sato N, Masumori N, Torigoe T. Inoue R, et al. Oncotarget. 2017 Apr 25;8(17):28826-28839. doi: 10.18632/oncotarget.16259. Oncotarget. 2017. PMID: 28418868 Free PMC article.
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are small sub-population of cancer cells that are endowed with higher tumor-initiating ability, self-renewal ability and differentiation ability. ...GRIK2 gene knockdown by siRNAs decreased t …
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are small sub-population of cancer cells that are endowed …
Identification of recurrent fusion genes across multiple cancer types.
Yu YP, Liu P, Nelson J, Hamilton RL, Bhargava R, Michalopoulos G, Chen Q, Zhang J, Ma D, Pennathur A, Luketich J, Nalesnik M, Tseng G, Luo JH. Yu YP, et al. Sci Rep. 2019 Jan 31;9(1):1074. doi: 10.1038/s41598-019-38550-6. Sci Rep. 2019. PMID: 30705370 Free PMC article.
Chromosome changes are one of the hallmarks of human malignancies. Chromosomal rearrangement is frequent in human cancers. One of the consequences of chromosomal rearrangement is gene fusions in the cancer genome. ...Among them, the CCNH-C5orf30 and TRMT11-GRIK2 …
Chromosome changes are one of the hallmarks of human malignancies. Chromosomal rearrangement is frequent in human cancers. One of the …
Isoforms of Ionotropic Glutamate Receptor GRIK2 Induce Senescence of Carcinoma Cells.
Zhawar VK, Kandpal RP, Athwal RS. Zhawar VK, et al. Cancer Genomics Proteomics. 2019 Jan-Feb;16(1):59-64. doi: 10.21873/cgp.20111. Cancer Genomics Proteomics. 2019. PMID: 30587499 Free PMC article.
MATERIALS AND METHODS: By using gene transfer technique, SKOV3 ovarian carcinoma cells were transduced with an expression construct of glutamate receptor 6 (glutamate ionotropic receptor kainate type subunit 2, GRIK2) in retroviral vector PQCXIP. The senescence of transduc …
MATERIALS AND METHODS: By using gene transfer technique, SKOV3 ovarian carcinoma cells were transduced with an expression construct of gluta …
Alternative Promoters of GRIK2 (GluR6) Gene in Human Carcinoma Cell Lines Are Regulated by Differential Methylation of CpG Dinucleotides.
Zhawar VK, Kandpal RP, Athwal RS. Zhawar VK, et al. Genes (Basel). 2022 Mar 10;13(3):490. doi: 10.3390/genes13030490. Genes (Basel). 2022. PMID: 35328043 Free PMC article.
The ionotropic glutamate receptor 6 (GluR6 or GRIK2) gene is transcribed by two cell-type-specific promoters in neuronal and non-neuronal cells, which results in five different transcript variants. ...
The ionotropic glutamate receptor 6 (GluR6 or GRIK2) gene is transcribed by two cell-type-specific promoters in neuronal and non-neur …
Gene polymorphisms and oral cancer risk in tobacco habitues.
Multani S, Pradhan S, Saranath D. Multani S, et al. Tumour Biol. 2016 May;37(5):6169-76. doi: 10.1007/s13277-015-4448-1. Epub 2015 Nov 27. Tumour Biol. 2016. PMID: 26614431
Oral cancer incidence of 77,003 poses a major health concern in India, with 5-10 % tobacco habitues developing oral cancer. ...The SNPs rs2124437 (RASGRP3), rs1335022 (GRIK2), rs4512367 (PREX2), rs4748011 (CCDC3), and rs1435218 (LNX1) were analyzed in 500 his …
Oral cancer incidence of 77,003 poses a major health concern in India, with 5-10 % tobacco habitues developing oral cancer. .. …
Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2.
Zhawar VK, Kandpal RP, Athwal RS. Zhawar VK, et al. Cancer Genomics Proteomics. 2020 Nov-Dec;17(6):707-714. doi: 10.21873/cgp.20225. Cancer Genomics Proteomics. 2020. PMID: 33099472 Free PMC article.
BACKGROUND/AIM: Glutamate receptor GRIK2, previously designated as GluR6, is best described in neuronal cells. ...RESULTS: The expression of GRIK2-A isoform led to immediate cessation of cell proliferation. ...
BACKGROUND/AIM: Glutamate receptor GRIK2, previously designated as GluR6, is best described in neuronal cells. ...RESULTS: The expres …
Glutamate receptor, ionotropic, kainate 2 silencing by DNA hypermethylation possesses tumor suppressor function in gastric cancer.
Wu CS, Lu YJ, Li HP, Hsueh C, Lu CY, Leu YW, Liu HP, Lin KH, Hui-Ming Huang T, Chang YS. Wu CS, et al. Int J Cancer. 2010 Jun 1;126(11):2542-52. doi: 10.1002/ijc.24958. Int J Cancer. 2010. PMID: 19824040 Free article.
Functional studies further showed that GRIK2-expressing gastric cancer cell lines showed decreased colony formation and cell migration. Taken together, these results suggest that GRIK2 may play a tumor-suppressor role in gastric cancer. Future studies …
Functional studies further showed that GRIK2-expressing gastric cancer cell lines showed decreased colony formation and cell m …
29 results