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19 results

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Page 1
Epigenetic scores of blood-based proteins as biomarkers of general cognitive function and brain health.
Smith HM, Moodie JE, Monterrubio-Gómez K, Gadd DA, Hillary RF, Chybowska AD, McCartney DL, Campbell A, Redmond P, Page D, Taylor A, Corley J, Harris SE, Valdés Hernández M, Muñoz Maniega S, Bastin ME, Wardlaw JM, Deary IJ, Boardman JP, Mullin DS, Russ TC, Cox SR, Marioni RE. Smith HM, et al. Among authors: gadd da. Clin Epigenetics. 2024 Mar 25;16(1):46. doi: 10.1186/s13148-024-01661-7. Clin Epigenetics. 2024. PMID: 38528588 Free PMC article.
Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6.
Stevenson AJ, Gadd DA, Hillary RF, McCartney DL, Campbell A, Walker RM, Evans KL, Harris SE, Spires-Jones TL, McRae AF, Visscher PM, McIntosh AM, Deary IJ, Marioni RE. Stevenson AJ, et al. Among authors: gadd da. J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2284-2292. doi: 10.1093/gerona/glab046. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33595649 Free PMC article.
Epigenetic predictors of lifestyle traits applied to the blood and brain.
Gadd DA, Stevenson AJ, Hillary RF, McCartney DL, Wrobel N, McCafferty S, Murphy L, Russ TC, Harris SE, Redmond P, Taylor AM, Smith C, Rose J, Millar T, Spires-Jones TL, Cox SR, Marioni RE. Gadd DA, et al. Brain Commun. 2021 Apr 19;3(2):fcab082. doi: 10.1093/braincomms/fcab082. eCollection 2021. Brain Commun. 2021. PMID: 34041477 Free PMC article.
Epigenetic scores for the circulating proteome as tools for disease prediction.
Gadd DA, Hillary RF, McCartney DL, Zaghlool SB, Stevenson AJ, Cheng Y, Fawns-Ritchie C, Nangle C, Campbell A, Flaig R, Harris SE, Walker RM, Shi L, Tucker-Drob EM, Gieger C, Peters A, Waldenberger M, Graumann J, McRae AF, Deary IJ, Porteous DJ, Hayward C, Visscher PM, Cox SR, Evans KL, McIntosh AM, Suhre K, Marioni RE. Gadd DA, et al. Elife. 2022 Jan 13;11:e71802. doi: 10.7554/eLife.71802. Elife. 2022. PMID: 35023833 Free PMC article.
Blood-based epigenome-wide analyses of cognitive abilities.
McCartney DL, Hillary RF, Conole ELS, Banos DT, Gadd DA, Walker RM, Nangle C, Flaig R, Campbell A, Murray AD, Maniega SM, Valdés-Hernández MDC, Harris MA, Bastin ME, Wardlaw JM, Harris SE, Porteous DJ, Tucker-Drob EM, McIntosh AM, Evans KL, Deary IJ, Cox SR, Robinson MR, Marioni RE. McCartney DL, et al. Among authors: gadd da. Genome Biol. 2022 Jan 17;23(1):26. doi: 10.1186/s13059-021-02596-5. Genome Biol. 2022. PMID: 35039062 Free PMC article.
A comparison of blood and brain-derived ageing and inflammation-related DNA methylation signatures and their association with microglial burdens.
Stevenson AJ, McCartney DL, Gadd DA, Shireby G, Hillary RF, King D, Tzioras M, Wrobel N, McCafferty S, Murphy L, McColl BW, Redmond P, Taylor AM, Harris SE, Russ TC, McIntosh AM, Mill J, Smith C, Deary IJ, Cox SR, Marioni RE, Spires-Jones TL. Stevenson AJ, et al. Among authors: gadd da. Eur J Neurosci. 2022 Nov;56(9):5637-5649. doi: 10.1111/ejn.15661. Epub 2022 Apr 6. Eur J Neurosci. 2022. PMID: 35362642 Free PMC article.
Genome- and epigenome-wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk.
Hillary RF, Gadd DA, McCartney DL, Shi L, Campbell A, Walker RM, Ritchie CW, Deary IJ, Evans KL, Nevado-Holgado AJ, Hayward C, Porteous DJ, McIntosh AM, Lovestone S, Robinson MR, Marioni RE. Hillary RF, et al. Among authors: gadd da. Alzheimers Dement (Amst). 2022 Apr 20;14(1):e12280. doi: 10.1002/dad2.12280. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35475137 Free PMC article.
Integrated methylome and phenome study of the circulating proteome reveals markers pertinent to brain health.
Gadd DA, Hillary RF, McCartney DL, Shi L, Stolicyn A, Robertson NA, Walker RM, McGeachan RI, Campbell A, Xueyi S, Barbu MC, Green C, Morris SW, Harris MA, Backhouse EV, Wardlaw JM, Steele JD, Oyarzún DA, Muniz-Terrera G, Ritchie C, Nevado-Holgado A, Chandra T, Hayward C, Evans KL, Porteous DJ, Cox SR, Whalley HC, McIntosh AM, Marioni RE. Gadd DA, et al. Nat Commun. 2022 Aug 9;13(1):4670. doi: 10.1038/s41467-022-32319-8. Nat Commun. 2022. PMID: 35945220 Free PMC article.
Refining epigenetic prediction of chronological and biological age.
Bernabeu E, McCartney DL, Gadd DA, Hillary RF, Lu AT, Murphy L, Wrobel N, Campbell A, Harris SE, Liewald D, Hayward C, Sudlow C, Cox SR, Evans KL, Horvath S, McIntosh AM, Robinson MR, Vallejos CA, Marioni RE. Bernabeu E, et al. Among authors: gadd da. Genome Med. 2023 Feb 28;15(1):12. doi: 10.1186/s13073-023-01161-y. Genome Med. 2023. PMID: 36855161 Free PMC article.
Blood-based epigenome-wide analyses of 19 common disease states: A longitudinal, population-based linked cohort study of 18,413 Scottish individuals.
Hillary RF, McCartney DL, Smith HM, Bernabeu E, Gadd DA, Chybowska AD, Cheng Y, Murphy L, Wrobel N, Campbell A, Walker RM, Hayward C, Evans KL, McIntosh AM, Marioni RE. Hillary RF, et al. Among authors: gadd da. PLoS Med. 2023 Jul 6;20(7):e1004247. doi: 10.1371/journal.pmed.1004247. eCollection 2023 Jul. PLoS Med. 2023. PMID: 37410739 Free PMC article. Review.
19 results