Gaedigk A - Search Results

1

Erratum: Constellation: a tool for rapid, automated phenotype assignment of a highly polymorphic pharmacogene, CYP2D6, from whole-genome sequences.

Twist GP, Gaedigk A, Miller NA, Farrow EG, Willig LK, Dinwiddie DL, Petrikin JE, Soden SE, Herd S, Gibson M, Cakici JA, Riffel AK, Leeder JS, Dinakarpandian D, Kingsmore SF. Twist GP, et al. Among authors: gaedigk a. NPJ Genom Med. 2017 Jan 11;2:16039. doi: 10.1038/npjgenmed.2016.39. eCollection 2017. NPJ Genom Med. 2017. PMID: 29266105 Free PMC article.

2

Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase.

Gaedigk A, Leeder JS, Grant DM. Gaedigk A, et al. DNA Cell Biol. 1997 Nov;16(11):1257-66. doi: 10.1089/dna.1997.16.1257. DNA Cell Biol. 1997. PMID: 9406998

3

High frequency of CYP2D6 poor and "intermediate" metabolizers in black populations: a review and preliminary data.

Bradford LD, Gaedigk A, Leeder JS. Bradford LD, et al. Among authors: gaedigk a. Psychopharmacol Bull. 1998;34(4):797-804. Psychopharmacol Bull. 1998. PMID: 10513455 Review.

4

Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.

Gaedigk A, Bradford LD, Marcucci KA, Leeder JS. Gaedigk A, et al. Clin Pharmacol Ther. 2002 Jul;72(1):76-89. doi: 10.1067/mcp.2002.125783. Clin Pharmacol Ther. 2002. PMID: 12152006 Clinical Trial.

5

CYP2D6 poor metabolizer status can be ruled out by a single genotyping assay for the -1584G promoter polymorphism.

Gaedigk A, Ryder DL, Bradford LD, Leeder JS. Gaedigk A, et al. Clin Chem. 2003 Jun;49(6 Pt 1):1008-11. doi: 10.1373/49.6.1008. Clin Chem. 2003. PMID: 12766015 No abstract available.

6

CYP2D7 splice variants in human liver and brain: does CYP2D7 encode functional protein?

Gaedigk A, Gaedigk R, Leeder JS. Gaedigk A, et al. Among authors: gaedigk r. Biochem Biophys Res Commun. 2005 Nov 4;336(4):1241-50. doi: 10.1016/j.bbrc.2005.08.255. Biochem Biophys Res Commun. 2005. PMID: 16169517

7

CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status.

Gaedigk A, Bradford LD, Alander SW, Leeder JS. Gaedigk A, et al. Drug Metab Dispos. 2006 Apr;34(4):563-9. doi: 10.1124/dmd.105.008292. Epub 2006 Jan 13. Drug Metab Dispos. 2006. PMID: 16415111

8

Comments on Hoskins et al. [(2005) drug metab dispos 33:1564-1565].

Gaedigk A, Leeder JS. Gaedigk A, et al. Drug Metab Dispos. 2006 Mar;34(3):504-5; author reply 506. doi: 10.1124/dmd.105.007799. Drug Metab Dispos. 2006. PMID: 16495382 No abstract available.

9

Evaluation of a [13C]-dextromethorphan breath test to assess CYP2D6 phenotype.

Leeder JS, Pearce RE, Gaedigk A, Modak A, Rosen DI. Leeder JS, et al. Among authors: gaedigk a. J Clin Pharmacol. 2008 Sep;48(9):1041-51. doi: 10.1177/0091270008319709. J Clin Pharmacol. 2008. PMID: 18728242 Free PMC article.

10

CYP2D7-2D6 hybrid tandems: identification of novel CYP2D6 duplication arrangements and implications for phenotype prediction.

Gaedigk A, Fuhr U, Johnson C, Bérard LA, Bradford D, Leeder JS. Gaedigk A, et al. Pharmacogenomics. 2010 Jan;11(1):43-53. doi: 10.2217/pgs.09.133. Pharmacogenomics. 2010. PMID: 20017671 Free PMC article.

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