Gaedigk A - Search Results

1

Advancing CYP2D6 Pharmacogenetics through a Pharmacoequity Lens.

Kehinde O, Ramsey LB, Gaedigk A, Oni-Orisan A. Kehinde O, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2023 Jul;114(1):69-76. doi: 10.1002/cpt.2890. Epub 2023 Apr 11. Clin Pharmacol Ther. 2023. PMID: 36924260 Review.

2

Interethnic differences of drug-metabolizing enzymes.

Gaedigk A. Gaedigk A. Int J Clin Pharmacol Ther. 2000 Feb;38(2):61-8. doi: 10.5414/cpp38061. Int J Clin Pharmacol Ther. 2000. PMID: 10706192 Review.

3

Concordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.

Abdel-Rahman SM, Leeder JS, Wilson JT, Gaedigk A, Gotschall RR, Medve R, Liao S, Spielberg SP, Kearns GL. Abdel-Rahman SM, et al. Among authors: gaedigk a. J Clin Pharmacol. 2002 Jan;42(1):24-9. doi: 10.1177/0091270002042001002. J Clin Pharmacol. 2002. PMID: 11808821

4

Unique CYP2D6 activity distribution and genotype-phenotype discordance in black Americans.

Gaedigk A, Bradford LD, Marcucci KA, Leeder JS. Gaedigk A, et al. Clin Pharmacol Ther. 2002 Jul;72(1):76-89. doi: 10.1067/mcp.2002.125783. Clin Pharmacol Ther. 2002. PMID: 12152006 Clinical Trial.

5

Activities of cytochrome P450 1A2, N-acetyltransferase 2, xanthine oxidase, and cytochrome P450 2D6 are unaltered in children with cystic fibrosis.

Kennedy MJ, Scripture CD, Kashuba AD, Scott CS, Gaedigk A, Kearns GL. Kennedy MJ, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2004 Mar;75(3):163-71. doi: 10.1016/j.clpt.2003.10.005. Clin Pharmacol Ther. 2004. PMID: 15001967

6

Cytochrome P4502D6 (CYP2D6) gene locus heterogeneity: characterization of gene duplication events.

Gaedigk A, Ndjountché L, Divakaran K, Dianne Bradford L, Zineh I, Oberlander TF, Brousseau DC, McCarver DG, Johnson JA, Alander SW, Wayne Riggs K, Steven Leeder J. Gaedigk A, et al. Clin Pharmacol Ther. 2007 Feb;81(2):242-51. doi: 10.1038/sj.clpt.6100033. Clin Pharmacol Ther. 2007. PMID: 17259947

7

Ontogeny of dextromethorphan O- and N-demethylation in the first year of life.

Blake MJ, Gaedigk A, Pearce RE, Bomgaars LR, Christensen ML, Stowe C, James LP, Wilson JT, Kearns GL, Leeder JS. Blake MJ, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2007 Apr;81(4):510-6. doi: 10.1038/sj.clpt.6100101. Epub 2007 Feb 14. Clin Pharmacol Ther. 2007. PMID: 17301735

8

Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype.

Gaedigk A, Eklund JD, Pearce RE, Leeder JS, Alander SW, Phillips MS, Bradford LD, Kennedy MJ. Gaedigk A, et al. Clin Pharmacol Ther. 2007 Jun;81(6):817-20. doi: 10.1038/sj.clpt.6100125. Epub 2007 Mar 28. Clin Pharmacol Ther. 2007. PMID: 17392730

9

The CYP2D6 activity score: translating genotype information into a qualitative measure of phenotype.

Gaedigk A, Simon SD, Pearce RE, Bradford LD, Kennedy MJ, Leeder JS. Gaedigk A, et al. Clin Pharmacol Ther. 2008 Feb;83(2):234-42. doi: 10.1038/sj.clpt.6100406. Epub 2007 Oct 31. Clin Pharmacol Ther. 2008. PMID: 17971818

10

Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan.

Abduljalil K, Frank D, Gaedigk A, Klaassen T, Tomalik-Scharte D, Jetter A, Jaehde U, Kirchheiner J, Fuhr U. Abduljalil K, et al. Among authors: gaedigk a. Clin Pharmacol Ther. 2010 Nov;88(5):643-51. doi: 10.1038/clpt.2010.137. Epub 2010 Sep 29. Clin Pharmacol Ther. 2010. PMID: 20881950 Free article.

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