Galea GL - Search Results

1

Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle.

Galea GL, Meakin LB, Harris MA, Delisser PJ, Lanyon LE, Harris SE, Price JS. Galea GL, et al. Gene. 2017 Jan 30;599:36-52. doi: 10.1016/j.gene.2016.11.006. Epub 2016 Nov 10. Gene. 2017. PMID: 27840164 Free PMC article.

2

Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice.

Sugiyama T, Galea GL, Lanyon LE, Price JS. Sugiyama T, et al. Among authors: galea gl. Endocrinology. 2010 Dec;151(12):5582-90. doi: 10.1210/en.2010-0645. Epub 2010 Oct 13. Endocrinology. 2010. PMID: 20943807 Free PMC article.

3

Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading.

Price JS, Sugiyama T, Galea GL, Meakin LB, Sunters A, Lanyon LE. Price JS, et al. Among authors: galea gl. Curr Osteoporos Rep. 2011 Jun;9(2):76-82. doi: 10.1007/s11914-011-0050-7. Curr Osteoporos Rep. 2011. PMID: 21384138 Review.

4

Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice.

Sugiyama T, Meakin LB, Galea GL, Jackson BF, Lanyon LE, Ebetino FH, Russell RG, Price JS. Sugiyama T, et al. Among authors: galea gl. Bone. 2011 Jul;49(1):133-9. doi: 10.1016/j.bone.2011.03.775. Epub 2011 Apr 9. Bone. 2011. PMID: 21497678 Free PMC article.

5

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4.

Galea GL, Sunters A, Meakin LB, Zaman G, Sugiyama T, Lanyon LE, Price JS. Galea GL, et al. FEBS Lett. 2011 Aug 4;585(15):2450-4. doi: 10.1016/j.febslet.2011.06.019. Epub 2011 Jun 28. FEBS Lett. 2011. PMID: 21723865 Free PMC article.

6

Zaman G, Sunters A, Galea GL, Javaheri B, Saxon LK, Moustafa A, Armstrong VJ, Price JS, Lanyon LE. Zaman G, et al. Among authors: galea gl. J Biol Chem. 2012 Feb 3;287(6):3946-62. doi: 10.1074/jbc.M111.252742. Epub 2011 Nov 2. J Biol Chem. 2012. PMID: 22049075 Free PMC article.

7

The cyclooxygenase-2 selective inhibitor NS-398 does not influence trabecular or cortical bone gain resulting from repeated mechanical loading in female mice.

Sugiyama T, Meakin LB, Galea GL, Lanyon LE, Price JS. Sugiyama T, et al. Among authors: galea gl. Osteoporos Int. 2013 Jan;24(1):383-8. doi: 10.1007/s00198-012-1922-0. Epub 2012 Feb 14. Osteoporos Int. 2013. PMID: 22349912 Free PMC article.

8

Estrogen receptors α and β have different gender-dependent effects on the adaptive responses to load bearing in cancellous and cortical bone.

Saxon LK, Galea G, Meakin L, Price J, Lanyon LE. Saxon LK, et al. Endocrinology. 2012 May;153(5):2254-66. doi: 10.1210/en.2011-1977. Epub 2012 Mar 13. Endocrinology. 2012. PMID: 22416084

9

Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition.

Sugiyama T, Meakin LB, Browne WJ, Galea GL, Price JS, Lanyon LE. Sugiyama T, et al. Among authors: galea gl. J Bone Miner Res. 2012 Aug;27(8):1784-93. doi: 10.1002/jbmr.1599. J Bone Miner Res. 2012. PMID: 22431329 Free PMC article.

10

Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.

Windahl SH, Saxon L, Börjesson AE, Lagerquist MK, Frenkel B, Henning P, Lerner UH, Galea GL, Meakin LB, Engdahl C, Sjögren K, Antal MC, Krust A, Chambon P, Lanyon LE, Price JS, Ohlsson C. Windahl SH, et al. Among authors: galea gl. J Bone Miner Res. 2013 Feb;28(2):291-301. doi: 10.1002/jbmr.1754. J Bone Miner Res. 2013. PMID: 22972752 Free PMC article.

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