Gandhi A - Search Results

1

Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes.

Ghose R, Guo T, Vallejo JG, Gandhi A. Ghose R, et al. Among authors: gandhi a. Drug Metab Dispos. 2011 May;39(5):874-81. doi: 10.1124/dmd.110.037382. Epub 2011 Feb 8. Drug Metab Dispos. 2011. PMID: 21303924 Free PMC article.

2

CYP3A-dependent drug metabolism is reduced in bacterial inflammation in mice.

Gandhi AS, Guo T, Shah P, Moorthy B, Chow DS, Hu M, Ghose R. Gandhi AS, et al. Br J Pharmacol. 2012 Aug;166(7):2176-87. doi: 10.1111/j.1476-5381.2012.01933.x. Br J Pharmacol. 2012. PMID: 22394353 Free PMC article.

3

Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters.

Ghose R, Omoluabi O, Gandhi A, Shah P, Strohacker K, Carpenter KC, McFarlin B, Guo T. Ghose R, et al. Among authors: gandhi a. Life Sci. 2011 Jul 4;89(1-2):57-64. doi: 10.1016/j.lfs.2011.05.005. Epub 2011 May 18. Life Sci. 2011. PMID: 21620874 Free PMC article.

4

Drug disposition in pathophysiological conditions.

Gandhi A, Moorthy B, Ghose R. Gandhi A, et al. Curr Drug Metab. 2012 Nov;13(9):1327-44. doi: 10.2174/138920012803341302. Curr Drug Metab. 2012. PMID: 22746301 Free PMC article. Review.

5

Chlorpromazine-induced hepatotoxicity during inflammation is mediated by TIRAP-dependent signaling pathway in mice.

Gandhi A, Guo T, Shah P, Moorthy B, Ghose R. Gandhi A, et al. Toxicol Appl Pharmacol. 2013 Feb 1;266(3):430-8. doi: 10.1016/j.taap.2012.11.030. Epub 2012 Dec 11. Toxicol Appl Pharmacol. 2013. PMID: 23238562 Free PMC article.

6

Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes.

Gandhi A, Guo T, Ghose R. Gandhi A, et al. J Toxicol Sci. 2010 Apr;35(2):163-73. doi: 10.2131/jts.35.163. J Toxicol Sci. 2010. PMID: 20371967 Free article.

7

Impact of obesity on accumulation of the toxic irinotecan metabolite, SN-38, in mice.

Mallick P, Shah P, Gandhi A, Ghose R. Mallick P, et al. Among authors: gandhi a. Life Sci. 2015 Oct 15;139:132-8. doi: 10.1016/j.lfs.2015.08.017. Epub 2015 Sep 1. Life Sci. 2015. PMID: 26334566

8

Quantitative analysis of lipids: a higher-throughput LC-MS/MS-based method and its comparison to ELISA.

Gandhi AS, Budac D, Khayrullina T, Staal R, Chandrasena G. Gandhi AS, et al. Future Sci OA. 2017 Jan 16;3(1):FSO157. doi: 10.4155/fsoa-2016-0067. eCollection 2017 Mar. Future Sci OA. 2017. PMID: 28344822 Free PMC article.

9

P2X7 receptor-mediated release of microglial prostanoids and miRNAs correlates with reversal of neuropathic hypersensitivity in rats.

Staal R, Khayrullina T, Christensen R, Hestehave S, Zhou H, Cajina M, Nattini ME, Gandhi A, Fallon SM, Schmidt M, Zorn SH, Brodbeck RM, Chandrasena G, Segerdahl M, Breysse N, Hopper AT, Möller T, Munro G. Staal R, et al. Among authors: gandhi a. Eur J Pain. 2022 Jul;26(6):1304-1321. doi: 10.1002/ejp.1951. Epub 2022 Apr 22. Eur J Pain. 2022. PMID: 35388574

10

Synthesis and Characterization of the Novel Rodent-Active and CNS-Penetrant P2X7 Receptor Antagonist Lu AF27139.

Hopper AT, Juhl M, Hornberg J, Badolo L, Kilburn JP, Thougaard A, Smagin G, Song D, Calice L, Menon V, Dale E, Zhang H, Cajina M, Nattini ME, Gandhi A, Grenon M, Jones K, Khayrullina T, Chandrasena G, Thomsen C, Zorn SH, Brodbeck R, Poda SB, Staal R, Möller T. Hopper AT, et al. Among authors: gandhi a. J Med Chem. 2021 Apr 22;64(8):4891-4902. doi: 10.1021/acs.jmedchem.0c02249. Epub 2021 Apr 6. J Med Chem. 2021. PMID: 33822617

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