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ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1.
Gao G, Plaas A, Thompson VP, Jin S, Zuo F, Sandy JD. Gao G, et al. J Biol Chem. 2004 Mar 12;279(11):10042-51. doi: 10.1074/jbc.M312100200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14701864 Free article.
Additional thoughts on group A streptococci.
Yu D, Zheng Y, Gao GF, Yang Y. Yu D, et al. Among authors: gao gf. Lancet Microbe. 2024 May 6:S2666-5247(24)00099-5. doi: 10.1016/S2666-5247(24)00099-5. Online ahead of print. Lancet Microbe. 2024. PMID: 38723643 No abstract available.
6,188 results