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Mapping the position of DNA polymerase-bound DNA templates in a nanopore at 5 A resolution.
ACS Nano. 2009 Jun 23;3(6):1457-66. doi: 10.1021/nn900303g.
ACS Nano. 2009.
PMID: 19489560
Direct observation of translocation in individual DNA polymerase complexes.
Dahl JM, Mai AH, Cherf GM, Jetha NN, Garalde DR, Marziali A, Akeson M, Wang H, Lieberman KR.
Dahl JM, et al. Among authors: garalde dr.
J Biol Chem. 2012 Apr 13;287(16):13407-21. doi: 10.1074/jbc.M111.338418. Epub 2012 Feb 29.
J Biol Chem. 2012.
PMID: 22378784
Free PMC article.
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Distinct complexes of DNA polymerase I (Klenow fragment) for base and sugar discrimination during nucleotide substrate selection.
Garalde DR, Simon CA, Dahl JM, Wang H, Akeson M, Lieberman KR.
Garalde DR, et al.
J Biol Chem. 2011 Apr 22;286(16):14480-92. doi: 10.1074/jbc.M111.218750. Epub 2011 Feb 28.
J Biol Chem. 2011.
PMID: 21362617
Free PMC article.
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Reading canonical and modified nucleobases in 16S ribosomal RNA using nanopore native RNA sequencing.
Smith AM, Jain M, Mulroney L, Garalde DR, Akeson M.
Smith AM, et al. Among authors: garalde dr.
PLoS One. 2019 May 16;14(5):e0216709. doi: 10.1371/journal.pone.0216709. eCollection 2019.
PLoS One. 2019.
PMID: 31095620
Free PMC article.
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Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting.
Gorzynski JE, Goenka SD, Shafin K, Jensen TD, Fisk DG, Grove ME, Spiteri E, Pesout T, Monlong J, Baid G, Bernstein JA, Ceresnak S, Chang PC, Christle JW, Chubb H, Dalton KP, Dunn K, Garalde DR, Guillory J, Knowles JW, Kolesnikov A, Ma M, Moscarello T, Nattestad M, Perez M, Ruzhnikov MRZ, Samadi M, Setia A, Wright C, Wusthoff CJ, Xiong K, Zhu T, Jain M, Sedlazeck FJ, Carroll A, Paten B, Ashley EA.
Gorzynski JE, et al. Among authors: garalde dr.
N Engl J Med. 2022 Feb 17;386(7):700-702. doi: 10.1056/NEJMc2112090. Epub 2022 Jan 12.
N Engl J Med. 2022.
PMID: 35020984
No abstract available.
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Ultra-Rapid Nanopore Whole Genome Genetic Diagnosis of Dilated Cardiomyopathy in an Adolescent With Cardiogenic Shock.
Gorzynski JE, Goenka SD, Shafin K, Jensen TD, Fisk DG, Grove ME, Spiteri E, Pesout T, Monlong J, Bernstein JA, Ceresnak S, Chang PC, Christle JW, Chubb H, Dunn K, Garalde DR, Guillory J, Ruzhnikov MRZ, Wright C, Wusthoff CJ, Xiong K, Hollander SA, Berry GJ, Jain M, Sedlazeck FJ, Carroll A, Paten B, Ashley EA.
Gorzynski JE, et al. Among authors: garalde dr.
Circ Genom Precis Med. 2022 Apr;15(2):e003591. doi: 10.1161/CIRCGEN.121.003591. Epub 2022 Feb 8.
Circ Genom Precis Med. 2022.
PMID: 35133172
No abstract available.
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Accelerated identification of disease-causing variants with ultra-rapid nanopore genome sequencing.
Goenka SD, Gorzynski JE, Shafin K, Fisk DG, Pesout T, Jensen TD, Monlong J, Chang PC, Baid G, Bernstein JA, Christle JW, Dalton KP, Garalde DR, Grove ME, Guillory J, Kolesnikov A, Nattestad M, Ruzhnikov MRZ, Samadi M, Sethia A, Spiteri E, Wright CJ, Xiong K, Zhu T, Jain M, Sedlazeck FJ, Carroll A, Paten B, Ashley EA.
Goenka SD, et al. Among authors: garalde dr.
Nat Biotechnol. 2022 Jul;40(7):1035-1041. doi: 10.1038/s41587-022-01221-5. Epub 2022 Mar 28.
Nat Biotechnol. 2022.
PMID: 35347328
Free PMC article.
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Highly parallel direct RNA sequencing on an array of nanopores.
Garalde DR, Snell EA, Jachimowicz D, Sipos B, Lloyd JH, Bruce M, Pantic N, Admassu T, James P, Warland A, Jordan M, Ciccone J, Serra S, Keenan J, Martin S, McNeill L, Wallace EJ, Jayasinghe L, Wright C, Blasco J, Young S, Brocklebank D, Juul S, Clarke J, Heron AJ, Turner DJ.
Garalde DR, et al.
Nat Methods. 2018 Mar;15(3):201-206. doi: 10.1038/nmeth.4577. Epub 2018 Jan 15.
Nat Methods. 2018.
PMID: 29334379
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