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1,383 results

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Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway.
Shain AH, Garrido M, Botton T, Talevich E, Yeh I, Sanborn JZ, Chung J, Wang NJ, Kakavand H, Mann GJ, Thompson JF, Wiesner T, Roy R, Olshen AB, Gagnon A, Gray JW, Huh N, Hur JS, Busam KJ, Scolyer RA, Cho RJ, Murali R, Bastian BC. Shain AH, et al. Among authors: garrido m. Nat Genet. 2015 Oct;47(10):1194-9. doi: 10.1038/ng.3382. Epub 2015 Sep 7. Nat Genet. 2015. PMID: 26343386 Free PMC article.
KIT as a therapeutic target in melanoma.
Garrido MC, Bastian BC. Garrido MC, et al. J Invest Dermatol. 2010 Jan;130(1):20-7. doi: 10.1038/jid.2009.334. J Invest Dermatol. 2010. PMID: 19847190 Free PMC article.
Activating MET kinase rearrangements in melanoma and Spitz tumours.
Yeh I, Botton T, Talevich E, Shain AH, Sparatta AJ, de la Fouchardiere A, Mully TW, North JP, Garrido MC, Gagnon A, Vemula SS, McCalmont TH, LeBoit PE, Bastian BC. Yeh I, et al. Nat Commun. 2015 May 27;6:7174. doi: 10.1038/ncomms8174. Nat Commun. 2015. PMID: 26013381 Free PMC article.
Sunitinib therapy for melanoma patients with KIT mutations.
Minor DR, Kashani-Sabet M, Garrido M, O'Day SJ, Hamid O, Bastian BC. Minor DR, et al. Among authors: garrido m. Clin Cancer Res. 2012 Mar 1;18(5):1457-63. doi: 10.1158/1078-0432.CCR-11-1987. Epub 2012 Jan 18. Clin Cancer Res. 2012. PMID: 22261812
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC. Wiesner T, et al. Among authors: garrido m. Nat Commun. 2014;5:3116. doi: 10.1038/ncomms4116. Nat Commun. 2014. PMID: 24445538 Free PMC article.
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy.
Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC. Botton T, et al. Among authors: garrido mc. Pigment Cell Melanoma Res. 2013 Nov;26(6):845-51. doi: 10.1111/pcmr.12148. Epub 2013 Aug 19. Pigment Cell Melanoma Res. 2013. PMID: 23890088 Free PMC article.
NTRK3 kinase fusions in Spitz tumours.
Yeh I, Tee MK, Botton T, Shain AH, Sparatta AJ, Gagnon A, Vemula SS, Garrido MC, Nakamaru K, Isoyama T, McCalmont TH, LeBoit PE, Bastian BC. Yeh I, et al. J Pathol. 2016 Nov;240(3):282-290. doi: 10.1002/path.4775. J Pathol. 2016. PMID: 27477320 Free PMC article.
Mutations in GNA11 in uveal melanoma.
Van Raamsdonk CD, Griewank KG, Crosby MB, Garrido MC, Vemula S, Wiesner T, Obenauf AC, Wackernagel W, Green G, Bouvier N, Sozen MM, Baimukanova G, Roy R, Heguy A, Dolgalev I, Khanin R, Busam K, Speicher MR, O'Brien J, Bastian BC. Van Raamsdonk CD, et al. Among authors: garrido mc. N Engl J Med. 2010 Dec 2;363(23):2191-9. doi: 10.1056/NEJMoa1000584. Epub 2010 Nov 17. N Engl J Med. 2010. PMID: 21083380 Free PMC article.
1,383 results