Gauthier JW - Search Results

1

Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene.

Rosati RL, Da Silva Jardine P, Cameron KO, Thompson DD, Ke HZ, Toler SM, Brown TA, Pan LC, Ebbinghaus CF, Reinhold AR, Elliott NC, Newhouse BN, Tjoa CM, Sweetnam PM, Cole MJ, Arriola MW, Gauthier JW, Crawford DT, Nickerson DF, Pirie CM, Qi H, Simmons HA, Tkalcevic GT. Rosati RL, et al. Among authors: gauthier jw. J Med Chem. 1998 Jul 30;41(16):2928-31. doi: 10.1021/jm980048b. J Med Chem. 1998. PMID: 9685230 No abstract available.

2

Disposition and metabolism of the novel macrolide antibiotic CP-163505 in cattle.

Linhares MC, Harran LP, Strelevitz TJ, Gauthier JW, Cole MJ, Hassfurther RL, Risk JE. Linhares MC, et al. Among authors: gauthier jw. J Vet Pharmacol Ther. 1998 Apr;21(2):99-106. doi: 10.1046/j.1365-2885.1998.00125.x. J Vet Pharmacol Ther. 1998. PMID: 9597646

3

Ligands for the tyrosine kinase p56lck SH2 domain: discovery of potent dipeptide derivatives with monocharged, nonhydrolyzable phosphate replacements.

Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Ghiro E, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M, Betageri R, Cardozo M, Hickey ER, Ingraham R, Jakes S, Kabcenell A, Kirrane T, Lukas S, Patel U, Proudfoot J, Sharma R, Tong L, Moss N. Beaulieu PL, et al. J Med Chem. 1999 May 20;42(10):1757-66. doi: 10.1021/jm980676t. J Med Chem. 1999. PMID: 10346928

4

Phosphotyrosine-containing dipeptides as high-affinity ligands for the p56lck SH2 domain.

Llinaś-Brunet M, Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Ghiro E, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Betageri R, Cardozo M, Jakes S, Lukas S, Patel U, Proudfoot J, Moss N. Llinaś-Brunet M, et al. J Med Chem. 1999 Feb 25;42(4):722-9. doi: 10.1021/jm980612i. J Med Chem. 1999. PMID: 10052978

5

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents.

Moss N, Beaulieu P, Duceppe JS, Ferland JM, Gauthier J, Ghiro E, Goulet S, Grenier L, Llinas-Brunet M, Plante R, et al. Moss N, et al. J Med Chem. 1995 Sep 1;38(18):3617-23. doi: 10.1021/jm00018a022. J Med Chem. 1995. PMID: 7658449

6

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase with improved in vivo antiviral activity.

Moss N, Beaulieu P, Duceppe JS, Ferland JM, Garneau M, Gauthier J, Ghiro E, Goulet S, Guse I, Jaramillo J, Llinas-Brunet M, Malenfant E, Plante R, Poirier M, Soucy F, Wernic D, Yoakim C, Déziel R. Moss N, et al. J Med Chem. 1996 Oct 11;39(21):4173-80. doi: 10.1021/jm960324r. J Med Chem. 1996. PMID: 8863795

7

Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.

Beaulieu PL, Bös M, Bousquet Y, Fazal G, Gauthier J, Gillard J, Goulet S, LaPlante S, Poupart MA, Lefebvre S, McKercher G, Pellerin C, Austel V, Kukolj G. Beaulieu PL, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):119-24. doi: 10.1016/j.bmcl.2003.10.023. Bioorg Med Chem Lett. 2004. PMID: 14684311

8

Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.

Beaulieu PL, Bousquet Y, Gauthier J, Gillard J, Marquis M, McKercher G, Pellerin C, Valois S, Kukolj G. Beaulieu PL, et al. J Med Chem. 2004 Dec 30;47(27):6884-92. doi: 10.1021/jm040134d. J Med Chem. 2004. PMID: 15615537

9

Ureido-based peptidomimetic inhibitor of herpes simplex virus ribonucleotide reductase: an investigation of inhibitor bioactive conformation.

Moss N, Beaulieu P, Duceppe JS, Ferland JM, Gauthier J, Ghiro E, Goulet S, Guse I, Llinàs-Brunet M, Plante R, Plamondon L, Wernic D, Déziel R. Moss N, et al. J Med Chem. 1996 May 24;39(11):2178-87. doi: 10.1021/jm950825x. J Med Chem. 1996. PMID: 8667361

10

Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.

Proudfoot JR, Betageri R, Cardozo M, Gilmore TA, Glynn S, Hickey ER, Jakes S, Kabcenell A, Kirrane TM, Tibolla AK, Lukas S, Patel UR, Sharma R, Yazdanian M, Moss N, Beaulieu PL, Cameron DR, Ferland JM, Gauthier J, Gillard J, Gorys V, Poirier M, Rancourt J, Wernic D, Llinas-Brunet M. Proudfoot JR, et al. J Med Chem. 2001 Jul 19;44(15):2421-31. doi: 10.1021/jm000446q. J Med Chem. 2001. PMID: 11448224

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