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Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML.
Jakobsen JS, Laursen LG, Schuster MB, Pundhir S, Schoof E, Ge Y, d'Altri T, Vitting-Seerup K, Rapin N, Gentil C, Jendholm J, Theilgaard-Mönch K, Reckzeh K, Bullinger L, Döhner K, Hokland P, Fitzgibbon J, Porse BT. Jakobsen JS, et al. Among authors: ge y. Sci Adv. 2019 Jul 10;5(7):eaaw4304. doi: 10.1126/sciadv.aaw4304. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31309149 Free PMC article.
PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents.
Rehn M, Wenzel A, Frank AK, Schuster MB, Pundhir S, Jørgensen N, Vitting-Seerup K, Ge Y, Jendholm J, Michaut M, Schoof EM, Jensen TL, Rapin N, Sapio RT, Andersen KL, Lund AH, Solimena M, Holzenberger M, Pestov DG, Porse BT. Rehn M, et al. Among authors: ge y. Cell Rep. 2022 May 10;39(6):110793. doi: 10.1016/j.celrep.2022.110793. Cell Rep. 2022. PMID: 35545054 Free article.
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes.
Trempenau ML, Schuster MB, Pundhir S, Pereira MA, Kalvisa A, Tapia M, Su J, Ge Y, de Boer B, Balhuizen A, Bagger FO, Shliaha P, Sroczynska P, Walfridsson J, Grønbæk K, Theilgaard-Mönch K, Jensen ON, Helin K, Porse BT. Trempenau ML, et al. Among authors: ge y. Leukemia. 2023 Mar;37(3):593-605. doi: 10.1038/s41375-023-01810-6. Epub 2023 Jan 12. Leukemia. 2023. PMID: 36631623 Free PMC article.
6,571 results