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2006 2
2008 2
2009 2
2012 1
2015 1
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2020 3
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22 results

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Page 1
Interplay Between Antibiotic Resistance and Virulence During Disease Promoted by Multidrug-Resistant Bacteria.
Geisinger E, Isberg RR. Geisinger E, et al. J Infect Dis. 2017 Feb 15;215(suppl_1):S9-S17. doi: 10.1093/infdis/jiw402. J Infect Dis. 2017. PMID: 28375515 Free PMC article. Review.
Diseases caused by antibiotic-resistant bacteria in hospitals are the outcome of complex relationships between several dynamic factors, including bacterial pathogenicity, the fitness costs of resistance in the human host, and selective forces resulting from interventions s …
Diseases caused by antibiotic-resistant bacteria in hospitals are the outcome of complex relationships between several dynamic factor …
Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice.
Huo W, Busch LM, Hernandez-Bird J, Hamami E, Marshall CW, Geisinger E, Cooper VS, van Opijnen T, Rosch JW, Isberg RR. Huo W, et al. Among authors: geisinger e. Nat Microbiol. 2022 Jun;7(6):796-809. doi: 10.1038/s41564-022-01126-8. Epub 2022 May 26. Nat Microbiol. 2022. PMID: 35618774 Free PMC article.
Acinetobacter baumannii is increasingly refractory to antibiotic treatment in healthcare settings. ...The genetic mechanism underlying both these results is initiated by mutations activating the drug egress pump regulator AdeL, which drives persistence in the presen …
Acinetobacter baumannii is increasingly refractory to antibiotic treatment in healthcare settings. ...The genetic mechanism un …
Quorum sensing in staphylococci.
Novick RP, Geisinger E. Novick RP, et al. Among authors: geisinger e. Annu Rev Genet. 2008;42:541-64. doi: 10.1146/annurev.genet.42.110807.091640. Annu Rev Genet. 2008. PMID: 18713030 Review.
Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability.
Geisinger E, Huo W, Hernandez-Bird J, Isberg RR. Geisinger E, et al. Annu Rev Microbiol. 2019 Sep 8;73:481-506. doi: 10.1146/annurev-micro-020518-115714. Epub 2019 Jun 14. Annu Rev Microbiol. 2019. PMID: 31206345 Review.
Acinetobacter baumannii has emerged as an important nosocomial pathogen, particularly for patients in intensive care units and with invasive indwelling devices. The most recent clinical isolates are resistant to several classes of clinically important antibiotics, g …
Acinetobacter baumannii has emerged as an important nosocomial pathogen, particularly for patients in intensive care units and with i …
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope.
Geisinger E, Mortman NJ, Dai Y, Cokol M, Syal S, Farinha A, Fisher DG, Tang AY, Lazinski DW, Wood S, Anthony J, van Opijnen T, Isberg RR. Geisinger E, et al. Nat Commun. 2020 Sep 9;11(1):4522. doi: 10.1038/s41467-020-18301-2. Nat Commun. 2020. PMID: 32908144 Free PMC article.
A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter baumannii. Here we use transposon insertion sequencing to identify A. baumannii mutants displaying altered susceptibility to a panel of diverse antibioti …
A unique, protective cell envelope contributes to the broad drug resistance of the nosocomial pathogen Acinetobacter baumannii. Here …
Genome-wide phage susceptibility analysis in Acinetobacter baumannii reveals capsule modulation strategies that determine phage infectivity.
Bai J, Raustad N, Denoncourt J, van Opijnen T, Geisinger E. Bai J, et al. Among authors: geisinger e. PLoS Pathog. 2023 Jun 8;19(6):e1010928. doi: 10.1371/journal.ppat.1010928. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37289824 Free PMC article.
Phage have gained renewed interest as an adjunctive treatment for life-threatening infections with the resistant nosocomial pathogen Acinetobacter baumannii. Our understanding of how A. baumannii defends against phage remains limited, although this information could lead t …
Phage have gained renewed interest as an adjunctive treatment for life-threatening infections with the resistant nosocomial pathogen Acin …
Antibiotic modulation of capsular exopolysaccharide and virulence in Acinetobacter baumannii.
Geisinger E, Isberg RR. Geisinger E, et al. PLoS Pathog. 2015 Feb 13;11(2):e1004691. doi: 10.1371/journal.ppat.1004691. eCollection 2015 Feb. PLoS Pathog. 2015. PMID: 25679516 Free PMC article.
Acinetobacter baumannii is an opportunistic pathogen of increasing importance due to its propensity for intractable multidrug-resistant infections in hospitals. ...Whether the polysaccharides determined by the K locus contribute to intrinsic defenses against antibiotics …
Acinetobacter baumannii is an opportunistic pathogen of increasing importance due to its propensity for intractable multidrug-resista …
Essential Gene Analysis in Acinetobacter baumannii by High-Density Transposon Mutagenesis and CRISPR Interference.
Bai J, Dai Y, Farinha A, Tang AY, Syal S, Vargas-Cuebas G, van Opijnen T, Isberg RR, Geisinger E. Bai J, et al. Among authors: geisinger e. J Bacteriol. 2021 May 20;203(12):e0056520. doi: 10.1128/JB.00565-20. Epub 2021 Mar 29. J Bacteriol. 2021. PMID: 33782056 Free PMC article.
Acinetobacter baumannii is a poorly understood bacterium capable of life-threatening infections in hospitals. Few antibiotics remain effective against this highly resistant pathogen. ...
Acinetobacter baumannii is a poorly understood bacterium capable of life-threatening infections in hospitals. Few antibiotics …
A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape.
Micelli C, Dai Y, Raustad N, Isberg RR, Dowson CG, Lloyd AJ, Geisinger E, Crow A, Roper DI. Micelli C, et al. Among authors: geisinger e. Proc Natl Acad Sci U S A. 2023 Feb 21;120(8):e2215237120. doi: 10.1073/pnas.2215237120. Epub 2023 Feb 14. Proc Natl Acad Sci U S A. 2023. PMID: 36787358 Free PMC article.
Acinetobacter baumannii is a gram-negative bacterial pathogen that causes challenging nosocomial infections. beta-lactam targeting of penicillin-binding protein (PBP)-mediated cell wall peptidoglycan (PG) formation is a well-established antimicrobial strategy. ...Due to th …
Acinetobacter baumannii is a gram-negative bacterial pathogen that causes challenging nosocomial infections. beta-lactam targeting of …
22 results