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Gentiana asclepiadea L. from Two High Mountainous Habitats: Inter- and Intrapopulation Variability Based on Species' Phytochemistry.
Popović Z, Krstić-Milošević D, Marković M, Vidaković V, Bojović S. Popović Z, et al. Plants (Basel). 2021 Jan 12;10(1):140. doi: 10.3390/plants10010140. Plants (Basel). 2021. PMID: 33445468 Free PMC article.
Natural populations of Gentiana asclepiadea L., located at two mountainous sites, were HPLC-analyzed regarding the contents of six representative secondary metabolites. ...The results of this study contribute to the spatiochemical profiling of G. asclepiadea …
Natural populations of Gentiana asclepiadea L., located at two mountainous sites, were HPLC-analyzed regarding the contents of …
Biological Activities and Chemical Profile of Gentiana asclepiadea and Inula helenium Ethanolic Extracts.
Buza V, Niculae M, Hanganu D, Pall E, Burtescu RF, Olah NK, Matei-Lațiu MC, Vlasiuc I, Iozon I, Szakacs AR, Ielciu I, Ștefănuț LC. Buza V, et al. Molecules. 2022 May 31;27(11):3560. doi: 10.3390/molecules27113560. Molecules. 2022. PMID: 35684497 Free PMC article.
This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic potential of ethanolic extracts obtained from Gentiana asclepiadea L. and Inula helenium L. roots, in relation to their chemical composition. ...
This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic potential of ethanolic extracts obtained from Gentiana …
Gentiana asclepiadea exerts antioxidant activity and enhances DNA repair of hydrogen peroxide- and silver nanoparticles-induced DNA damage.
Hudecová A, Kusznierewicz B, Hašplová K, Huk A, Magdolenová Z, Miadoková E, Gálová E, Dušinská M. Hudecová A, et al. Food Chem Toxicol. 2012 Sep;50(9):3352-9. doi: 10.1016/j.fct.2012.06.017. Epub 2012 Jun 18. Food Chem Toxicol. 2012. PMID: 22721983
Thus DNA repair is of great importance in preventing mutations and contributes crucially to the prevention of cancer. In our study we have focused on quantitative analysis of Gentiana asclepiadea aqueous or methanolic extracts obtained from flower and haulm, their a …
Thus DNA repair is of great importance in preventing mutations and contributes crucially to the prevention of cancer. In our study we have f …
Gentiana asclepiadea protects human cells against oxidation DNA lesions.
Hudecová A, Hašplová K, Miadoková E, Magdolenová Z, Rinna A, Collins AR, Gálová E, Vaculčíková D, Gregáň F, Dušinská M. Hudecová A, et al. Cell Biochem Funct. 2012 Mar;30(2):101-7. doi: 10.1002/cbf.1822. Epub 2011 Nov 28. Cell Biochem Funct. 2012. PMID: 22124976
The objectives of this study were to examine whether the methanolic and aqueous extracts from the haulm and flower of Gentiana asclepiadea exhibited free radical scavenging and protective (antigenotoxic) effect against DNA oxidation induced by H(2)O(2) in human lymp …
The objectives of this study were to examine whether the methanolic and aqueous extracts from the haulm and flower of Gentiana asc …
Gentiana asclepiadea and Armoracia rusticana can modulate the adaptive response induced by zeocin in human lymphocytes.
Hudecova A, Hasplova K, Kellovska L, Ikreniova M, Miadokova E, Galova E, Horvathova E, Vaculcikova D, Gregan F, Dusinska M. Hudecova A, et al. Neoplasma. 2012;59(1):62-9. doi: 10.4149/neo_2012_01_008. Neoplasma. 2012. PMID: 22103898
Genotoxic impact of zeocin to lymphocytes was modulated by plant extracts isolated from Gentiana asclepiadea (methanolic and aqueous haulm extracts, 0.25 mg/ml) and Armoracia rusticana (methanolic root extract, 0.025 mg/ml). ...
Genotoxic impact of zeocin to lymphocytes was modulated by plant extracts isolated from Gentiana asclepiadea (methanolic and a …
Hepatoprotective effects of Gentiana asclepiadea L. extracts against carbon tetrachloride induced liver injury in rats.
Mihailović V, Mihailović M, Uskoković A, Arambašić J, Mišić D, Stanković V, Katanić J, Mladenović M, Solujić S, Matić S. Mihailović V, et al. Food Chem Toxicol. 2013 Feb;52:83-90. doi: 10.1016/j.fct.2012.10.034. Epub 2012 Nov 9. Food Chem Toxicol. 2013. PMID: 23146698
This study is an attempt to evaluate the hepatoprotective activity of Gentiana asclepiadea L. against carbon tetrachloride-induced liver injury in rats. Methanol extracts of aerial parts (GAA) and roots (GAR) of G. asclepiadea at doses of 100, 200, and 400mg/ …
This study is an attempt to evaluate the hepatoprotective activity of Gentiana asclepiadea L. against carbon tetrachloride-ind …
Chemical composition, antioxidant and antigenotoxic activities of different fractions of Gentiana asclepiadea L. roots extract.
Mihailovic V, Matic S, Mišic D, Solujic S, Stanic S, Katanic J, Mladenovic M, Stankovic N. Mihailovic V, et al. EXCLI J. 2013 Sep 12;12:807-23. eCollection 2013. EXCLI J. 2013. PMID: 26622219 Free PMC article.
The aim of this study was to evaluate the antioxidant and antigenotoxic activities of chloroform, ethyl acetate and n-butanol fractions obtained from Gentiana asclepiadea L. roots methanolic extract. The main secondary metabolites sweroside, swertiamarin and gentiop …
The aim of this study was to evaluate the antioxidant and antigenotoxic activities of chloroform, ethyl acetate and n-butanol fractions obta …
Caucasian Gentiana Species: Untargeted LC-MS Metabolic Profiling, Antioxidant and Digestive Enzyme Inhibiting Activity of Six Plants.
Olennikov DN, Gadimli AI, Isaev JI, Kashchenko NI, Prokopyev AS, Kataeva TN, Chirikova NK, Vennos C. Olennikov DN, et al. Metabolites. 2019 Nov 7;9(11):271. doi: 10.3390/metabo9110271. Metabolites. 2019. PMID: 31703419 Free PMC article.
The members of Gentiana genus are widely distributed in the Caucasus region where they are used as phytoremedies, but they still have not been studied for their chemical composition and bioactivity. High-performance liquid chromatography with diode array and electrospray t …
The members of Gentiana genus are widely distributed in the Caucasus region where they are used as phytoremedies, but they still have …
Silver nanoparticles induce premutagenic DNA oxidation that can be prevented by phytochemicals from Gentiana asclepiadea.
Hudecová A, Kusznierewicz B, Rundén-Pran E, Magdolenová Z, Hasplová K, Rinna A, Fjellsbø LM, Kruszewski M, Lankoff A, Sandberg WJ, Refsnes M, Skuland T, Schwarze P, Brunborg G, Bjøras M, Collins A, Miadoková E, Gálová E, Dusinská M. Hudecová A, et al. Mutagenesis. 2012 Nov;27(6):759-69. doi: 10.1093/mutage/ges046. Epub 2012 Sep 1. Mutagenesis. 2012. PMID: 22940646
Oxidised DNA base lesions and strand breaks caused by AgNPs were diminished by aqueous and methanolic extracts from both haulm and flower of Gentiana asclepiadea....
Oxidised DNA base lesions and strand breaks caused by AgNPs were diminished by aqueous and methanolic extracts from both haulm and flower of …
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