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Spatiotemporal immune atlas of the first clinical-grade, gene-edited pig-to-human kidney xenotransplant.
Cheung MD, Asiimwe R, Erman EN, Fucile CF, Liu S, Sun CW, Hanumanthu VS, Pal HC, Wright ED, Ghajar-Rahimi G, Epstein D, Orandi BJ, Kumar V, Anderson DJ, Greene ME, Bell M, Yates S, Moore KH, LaFontaine J, Killian JT Jr, Baker G, Perry J, Reed R, Little SC, Rosenberg AF, George JF, Locke JE, Porrett PM. Cheung MD, et al. Among authors: george jf. Res Sq [Preprint]. 2023 Jan 9:rs.3.rs-2382345. doi: 10.21203/rs.3.rs-2382345/v1. Res Sq. 2023. PMID: 36711785 Free PMC article. Updated. Preprint.
First clinical-grade porcine kidney xenotransplant using a human decedent model.
Porrett PM, Orandi BJ, Kumar V, Houp J, Anderson D, Cozette Killian A, Hauptfeld-Dolejsek V, Martin DE, Macedon S, Budd N, Stegner KL, Dandro A, Kokkinaki M, Kuravi KV, Reed RD, Fatima H, Killian JT Jr, Baker G, Perry J, Wright ED, Cheung MD, Erman EN, Kraebber K, Gamblin T, Guy L, George JF, Ayares D, Locke JE. Porrett PM, et al. Among authors: george jf. Am J Transplant. 2022 Apr;22(4):1037-1053. doi: 10.1111/ajt.16930. Epub 2022 Jan 20. Am J Transplant. 2022. PMID: 35049121 Free article.
Resident macrophage subpopulations occupy distinct microenvironments in the kidney.
Cheung MD, Erman EN, Moore KH, Lever JM, Li Z, LaFontaine JR, Ghajar-Rahimi G, Liu S, Yang Z, Karim R, Yoder BK, Agarwal A, George JF. Cheung MD, et al. Among authors: george jf. JCI Insight. 2022 Oct 24;7(20):e161078. doi: 10.1172/jci.insight.161078. JCI Insight. 2022. PMID: 36066976 Free PMC article.
Functional consequence of myeloid ferritin heavy chain on acute and chronic effects of rhabdomyolysis-induced kidney injury.
McCullough KR, Akhter J, Taheri MJ, Traylor A, Zmijewska AA, Verma V, Hudson MC, Sachdeva A, Erman EN, Moore KH, George JF, Bolisetty S. McCullough KR, et al. Among authors: george jf. Front Med (Lausanne). 2022 Sep 8;9:894521. doi: 10.3389/fmed.2022.894521. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36160140 Free PMC article.
Spatiotemporal immune atlas of a clinical-grade gene-edited pig-to-human kidney xenotransplant.
Cheung MD, Asiimwe R, Erman EN, Fucile CF, Liu S, Sun CW, Hanumanthu VS, Pal HC, Wright ED, Ghajar-Rahimi G, Epstein D, Orandi BJ, Kumar V, Anderson DJ, Greene ME, Bell M, Yates S, Moore KH, LaFontaine J, Killian JT Jr, Baker G, Perry J, Khan Z, Reed R, Little SC, Rosenberg AF, George JF, Locke JE, Porrett PM. Cheung MD, et al. Among authors: george jf. Nat Commun. 2024 Apr 11;15(1):3140. doi: 10.1038/s41467-024-47454-7. Nat Commun. 2024. PMID: 38605083 Free PMC article.
A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice.
Song CJ, Li Z, Ahmed UKB, Bland SJ, Yashchenko A, Liu S, Aloria EJ, Lever JM, Gonzalez NM, Bickel MA, Giles CB, Georgescu C, Wren JD, Lang ML, Benveniste EN, Harrington LE, Tsiokas L, George JF, Jones KL, Crossman DK, Agarwal A, Mrug M, Yoder BK, Hopp K, Zimmerman KA. Song CJ, et al. Among authors: george jf. J Am Soc Nephrol. 2022 Apr;33(4):747-768. doi: 10.1681/ASN.2021030278. Epub 2022 Feb 2. J Am Soc Nephrol. 2022. PMID: 35110364 Free PMC article.
Divergent effects of AKI to CKD models on inflammation and fibrosis.
Black LM, Lever JM, Traylor AM, Chen B, Yang Z, Esman SK, Jiang Y, Cutter GR, Boddu R, George JF, Agarwal A. Black LM, et al. Among authors: george jf. Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1107-F1118. doi: 10.1152/ajprenal.00179.2018. Epub 2018 Jun 13. Am J Physiol Renal Physiol. 2018. PMID: 29897282 Free PMC article.
Resident macrophages reprogram toward a developmental state after acute kidney injury.
Lever JM, Hull TD, Boddu R, Pepin ME, Black LM, Adedoyin OO, Yang Z, Traylor AM, Jiang Y, Li Z, Peabody JE, Eckenrode HE, Crossman DK, Crowley MR, Bolisetty S, Zimmerman KA, Wende AR, Mrug M, Yoder BK, Agarwal A, George JF. Lever JM, et al. Among authors: george jf. JCI Insight. 2019 Jan 24;4(2):e125503. doi: 10.1172/jci.insight.125503. JCI Insight. 2019. PMID: 30674729 Free PMC article.
143 results