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The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions.
Lund J, Breum AW, Gil C, Falk S, Sass F, Isidor MS, Dmytriyeva O, Ranea-Robles P, Mathiesen CV, Basse AL, Johansen OS, Fadahunsi N, Lund C, Nicolaisen TS, Klein AB, Ma T, Emanuelli B, Kleinert M, Sørensen CM, Gerhart-Hines Z, Clemmensen C. Lund J, et al. Among authors: gerhart hines z. Nat Metab. 2023 Apr;5(4):677-698. doi: 10.1038/s42255-023-00780-4. Epub 2023 Apr 13. Nat Metab. 2023. PMID: 37055619
Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge.
Emmett MJ, Lim HW, Jager J, Richter HJ, Adlanmerini M, Peed LC, Briggs ER, Steger DJ, Ma T, Sims CA, Baur JA, Pei L, Won KJ, Seale P, Gerhart-Hines Z, Lazar MA. Emmett MJ, et al. Nature. 2017 Jun 22;546(7659):544-548. doi: 10.1038/nature22819. Epub 2017 Jun 14. Nature. 2017. PMID: 28614293 Free PMC article.
Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis.
Sustarsic EG, Ma T, Lynes MD, Larsen M, Karavaeva I, Havelund JF, Nielsen CH, Jedrychowski MP, Moreno-Torres M, Lundh M, Plucinska K, Jespersen NZ, Grevengoed TJ, Kramar B, Peics J, Hansen JB, Shamsi F, Forss I, Neess D, Keipert S, Wang J, Stohlmann K, Brandslund I, Christensen C, Jørgensen ME, Linneberg A, Pedersen O, Kiebish MA, Qvortrup K, Han X, Pedersen BK, Jastroch M, Mandrup S, Kjær A, Gygi SP, Hansen T, Gillum MP, Grarup N, Emanuelli B, Nielsen S, Scheele C, Tseng YH, Færgeman NJ, Gerhart-Hines Z. Sustarsic EG, et al. Cell Metab. 2018 Jul 3;28(1):159-174.e11. doi: 10.1016/j.cmet.2018.05.003. Epub 2018 May 31. Cell Metab. 2018. PMID: 29861389 Free PMC article.
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue.
Lundh M, Petersen PS, Isidor MS, Kazoka-Sørensen DN, Plucińska K, Shamsi F, Ørskov C, Tozzi M, Brown EL, Andersen E, Ma T, Müller U, Barrès R, Kristiansen VB, Gerhart-Hines Z, Tseng YH, Emanuelli B. Lundh M, et al. EMBO Rep. 2019 Aug;20(8):e48216. doi: 10.15252/embr.201948216. Epub 2019 Jul 2. EMBO Rep. 2019. PMID: 31264358 Free PMC article.
Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine.
Deshmukh AS, Peijs L, Beaudry JL, Jespersen NZ, Nielsen CH, Ma T, Brunner AD, Larsen TJ, Bayarri-Olmos R, Prabhakar BS, Helgstrand C, Severinsen MCK, Holst B, Kjaer A, Tang-Christensen M, Sanfridson A, Garred P, Privé GG, Pedersen BK, Gerhart-Hines Z, Nielsen S, Drucker DJ, Mann M, Scheele C. Deshmukh AS, et al. Cell Metab. 2019 Nov 5;30(5):963-975.e7. doi: 10.1016/j.cmet.2019.10.001. Epub 2019 Oct 24. Cell Metab. 2019. PMID: 31668873 Free article.
Role of Energy Excretion in Human Body Weight Regulation.
Lund J, Gerhart-Hines Z, Clemmensen C. Lund J, et al. Trends Endocrinol Metab. 2020 Oct;31(10):705-708. doi: 10.1016/j.tem.2020.06.002. Epub 2020 Jul 13. Trends Endocrinol Metab. 2020. PMID: 32674987 Free article. Review.
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure.
Nicolaisen TS, Klein AB, Dmytriyeva O, Lund J, Ingerslev LR, Fritzen AM, Carl CS, Lundsgaard AM, Frost M, Ma T, Schjerling P, Gerhart-Hines Z, Flamant F, Gauthier K, Larsen S, Richter EA, Kiens B, Clemmensen C. Nicolaisen TS, et al. FASEB J. 2020 Nov;34(11):15480-15491. doi: 10.1096/fj.202001258RR. Epub 2020 Sep 23. FASEB J. 2020. PMID: 32969079 Free PMC article.
White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment.
Rabiee A, Plucińska K, Isidor MS, Brown EL, Tozzi M, Sidoli S, Petersen PSS, Agueda-Oyarzabal M, Torsetnes SB, Chehabi GN, Lundh M, Altıntaş A, Barrès R, Jensen ON, Gerhart-Hines Z, Emanuelli B. Rabiee A, et al. Mol Metab. 2021 Feb;44:101137. doi: 10.1016/j.molmet.2020.101137. Epub 2020 Dec 5. Mol Metab. 2021. PMID: 33285300 Free PMC article.
58 results