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A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Innocenti F, Owzar K, Cox NL, Evans P, Kubo M, Zembutsu H, Jiang C, Hollis D, Mushiroda T, Li L, Friedman P, Wang L, Glubb D, Hurwitz H, Giacomini KM, McLeod HL, Goldberg RM, Schilsky RL, Kindler HL, Nakamura Y, Ratain MJ. Innocenti F, et al. Among authors: giacomini km. Clin Cancer Res. 2012 Jan 15;18(2):577-84. doi: 10.1158/1078-0432.CCR-11-1387. Epub 2011 Dec 5. Clin Cancer Res. 2012. PMID: 22142827 Free PMC article.
Pharmacogenomics: challenges and opportunities.
Roden DM, Altman RB, Benowitz NL, Flockhart DA, Giacomini KM, Johnson JA, Krauss RM, McLeod HL, Ratain MJ, Relling MV, Ring HZ, Shuldiner AR, Weinshilboum RM, Weiss ST; Pharmacogenetics Research Network. Roden DM, et al. Among authors: giacomini km. Ann Intern Med. 2006 Nov 21;145(10):749-57. doi: 10.7326/0003-4819-145-10-200611210-00007. Ann Intern Med. 2006. PMID: 17116919 Free PMC article. Review.
Creating and evaluating genetic tests predictive of drug response.
Weiss ST, McLeod HL, Flockhart DA, Dolan ME, Benowitz NL, Johnson JA, Ratain MJ, Giacomini KM. Weiss ST, et al. Among authors: giacomini km. Nat Rev Drug Discov. 2008 Jul;7(7):568-74. doi: 10.1038/nrd2520. Epub 2008 Jun 20. Nat Rev Drug Discov. 2008. PMID: 18587383 Free PMC article. Review.
Pharmacogenomics and patient care: one size does not fit all.
Giacomini KM, Yee SW, Ratain MJ, Weinshilboum RM, Kamatani N, Nakamura Y. Giacomini KM, et al. Sci Transl Med. 2012 Sep 26;4(153):153ps18. doi: 10.1126/scitranslmed.3003471. Sci Transl Med. 2012. PMID: 23019654 Free PMC article. Review.
Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes.
Rotroff DM, Yee SW, Zhou K, Marvel SW, Shah HS, Jack JR, Havener TM, Hedderson MM, Kubo M, Herman MA, Gao H, Mychaleckyi JC, McLeod HL, Doria A, Giacomini KM, Pearson ER, Wagner MJ, Buse JB, Motsinger-Reif AA; MetGen Investigators; ACCORD/ACCORDion Investigators. Rotroff DM, et al. Among authors: giacomini km. Diabetes. 2018 Jul;67(7):1428-1440. doi: 10.2337/db17-1164. Epub 2018 Apr 12. Diabetes. 2018. PMID: 29650774 Free PMC article. Clinical Trial.
The pharmacogenetics research network: from SNP discovery to clinical drug response.
Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, Reus V, Roden DM, Schaefer CA, Shuldiner AR, Skaar T, Tantisira K, Tyndale RF, Wang L, Weinshilboum RM, Weiss ST, Zineh I; Pharmacogenetics Research Network. Giacomini KM, et al. Clin Pharmacol Ther. 2007 Mar;81(3):328-45. doi: 10.1038/sj.clpt.6100087. Clin Pharmacol Ther. 2007. PMID: 17339863 Free PMC article. Review.
344 results