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Bioorthogonal 4H-pyrazole "click" reagents.
Abularrage NS, Levandowski BJ, Giancola JB, Graham BJ, Raines RT. Abularrage NS, et al. Among authors: giancola jb. Chem Commun (Camb). 2023 Apr 11;59(30):4451-4454. doi: 10.1039/d3cc00112a. Chem Commun (Camb). 2023. PMID: 36987784 Free PMC article.
Structure-Activity Relationships for a Series of (Bis(4-fluorophenyl)methyl)sulfinyl Alkyl Alicyclic Amines at the Dopamine Transporter: Functionalizing the Terminal Nitrogen Affects Affinity, Selectivity, and Metabolic Stability.
Slack RD, Ku TC, Cao J, Giancola JB, Bonifazi A, Loland CJ, Gadiano A, Lam J, Rais R, Slusher BS, Coggiano M, Tanda G, Newman AH. Slack RD, et al. Among authors: giancola jb. J Med Chem. 2020 Mar 12;63(5):2343-2357. doi: 10.1021/acs.jmedchem.9b01188. Epub 2019 Nov 14. J Med Chem. 2020. PMID: 31661268 Free PMC article.
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter.
Slack RD, Abramyan AM, Tang H, Meena S, Davis BA, Bonifazi A, Giancola JB, Deschamps JR, Naing S, Yano H, Singh SK, Newman AH, Shi L. Slack RD, et al. Among authors: giancola jb. ACS Chem Neurosci. 2019 Sep 18;10(9):3946-3952. doi: 10.1021/acschemneuro.9b00375. Epub 2019 Aug 22. ACS Chem Neurosci. 2019. PMID: 31424193 Free PMC article.
Structure-activity relationships for a series of (Bis(4-fluorophenyl)methyl)sulfinylethyl-aminopiperidines and -piperidine amines at the dopamine transporter: Bioisosteric replacement of the piperazine improves metabolic stability.
Giancola JB, Bonifazi A, Cao J, Ku T, Haraczy AJ, Lam J, Rais R, Coggiano MA, Tanda G, Newman AH. Giancola JB, et al. Eur J Med Chem. 2020 Dec 15;208:112674. doi: 10.1016/j.ejmech.2020.112674. Epub 2020 Aug 9. Eur J Med Chem. 2020. PMID: 32947229 Free PMC article.
Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane.
Del Bello F, Micioni Di Bonaventura MV, Bonifazi A, Wünsch B, Schepmann D, Giancola JB, Micioni Di Bonaventura E, Vistoli G, Giorgioni G, Quaglia W, Piergentili A, Cifani C. Del Bello F, et al. Among authors: giancola jb. ACS Chem Neurosci. 2019 Aug 21;10(8):3391-3397. doi: 10.1021/acschemneuro.9b00261. Epub 2019 Jul 23. ACS Chem Neurosci. 2019. PMID: 31298830 Free article.