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Sequence requirements for cytochrome P-450IIB1 catalytic activity. Alteration of the stereospecificity and regioselectivity of steroid hydroxylation by a simultaneous change of two hydrophobic amino acid residues to phenylalanine.
Aoyama T, Korzekwa K, Nagata K, Adesnik M, Reiss A, Lapenson DP, Gillette J, Gelboin HV, Waxman DJ, Gonzalez FJ. Aoyama T, et al. Among authors: gillette j. J Biol Chem. 1989 Dec 15;264(35):21327-33. J Biol Chem. 1989. PMID: 2574176 Free article.
Isotope effect studies on the cytochrome P450 enzymes.
Korzekwa KR, Gillette JR, Trager WF. Korzekwa KR, et al. Among authors: gillette jr. Drug Metab Rev. 1995;27(1-2):45-59. doi: 10.3109/03602539509029814. Drug Metab Rev. 1995. PMID: 7641584 Review.
338 results