Gilmore J - Search Results

1

SAR development of a selective 5-HT1D antagonist/serotonin reuptake inhibitor lead using rapid parallel synthesis.

Timms GH, Boot JR, Broadmore RJ, Carney SL, Cooper J, Findlay JD, Gilmore J, Mitchell S, Moore NA, Pullar I, Sanger GJ, Tomlinson R, Tree BB, Wedley S. Timms GH, et al. Among authors: gilmore j. Bioorg Med Chem Lett. 2004 May 17;14(10):2469-72. doi: 10.1016/j.bmcl.2004.03.003. Bioorg Med Chem Lett. 2004. PMID: 15109634

2

Novel selective and potent 5-HT reuptake inhibitors with 5-HT1D antagonist activity: chemistry and pharmacological evaluation of a series of thienopyran derivatives.

Torrado A, Lamas C, Agejas J, Jiménez A, Diaz N, Gilmore J, Boot J, Findlay J, Hayhurst L, Wallace L, Broadmore R, Tomlinson R. Torrado A, et al. Among authors: gilmore j. Bioorg Med Chem. 2004 Oct 15;12(20):5277-95. doi: 10.1016/j.bmc.2004.07.059. Bioorg Med Chem. 2004. PMID: 15388156

3

Naphthyl piperazines with dual activity as 5-HT1D antagonists and 5-HT reuptake inhibitors.

Bueno AB, Gilmore J, Boot J, Broadmore R, Cooper J, Findlay J, Hayhurst L, Marcos A, Montero C, Mitchell S, Timms G, Tomlinson R, Wallace L, Walton L. Bueno AB, et al. Among authors: gilmore j. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3344-8. doi: 10.1016/j.bmcl.2007.03.101. Epub 2007 Apr 5. Bioorg Med Chem Lett. 2007. PMID: 17434731

4

N-Alkyl-N-arylmethylpiperidin-4-amines: novel dual inhibitors of serotonin and norepinephrine reuptake.

Boot JR, Boulet SL, Clark BP, Cases-Thomas MJ, Delhaye L, Diker K, Fairhurst J, Findlay J, Gallagher PT, Gilmore J, Harris JR, Masters JJ, Mitchell SN, Naik M, Simmonds RG, Smith SM, Richards SJ, Timms GH, Whatton MA, Wolfe CN, Wood VA. Boot JR, et al. Among authors: gilmore j. Bioorg Med Chem Lett. 2006 May 15;16(10):2714-8. doi: 10.1016/j.bmcl.2006.02.008. Epub 2006 Feb 23. Bioorg Med Chem Lett. 2006. PMID: 16497500

5

The pharmacology of LY290324 in the guinea-pig: an orally active, potent and selective cysteinyl leukotriene receptor antagonist.

Boot JR, Bond A, Thomas KH, O'Brien A, Gilmore J, Todd A. Boot JR, et al. Among authors: gilmore j. Eur J Pharmacol. 1993 Jan 26;231(1):83-9. doi: 10.1016/0014-2999(93)90687-d. Eur J Pharmacol. 1993. PMID: 8383064

6

LY393615, a novel neuronal Ca(2+) and Na(+) channel blocker with neuroprotective effects in models of in vitro and in vivo cerebral ischemia.

O'Neill MJ, Hicks CA, Ward MA, Osborne DJ, Wishart G, Mathews KS, McLaughlin DP, Stamford JA, McCarty DR, Patrick KE, Roman C, Fleisch JH, Gilmore J, Boot JR. O'Neill MJ, et al. Among authors: gilmore j. Brain Res. 2001 Jan 5;888(1):138-149. doi: 10.1016/s0006-8993(00)03043-2. Brain Res. 2001. PMID: 11146060

7

The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia.

Bath CP, Farrell LN, Gilmore J, Ward MA, Hicks CA, O'Neill MJ, Bleakman D. Bath CP, et al. Among authors: gilmore j. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12. doi: 10.1016/0014-2999(95)00846-2. Eur J Pharmacol. 1996. PMID: 8901012

8

Effects of Ca2+ and Na+ channel inhibitors in vitro and in global cerebral ischaemia in vivo.

O'Neill MJ, Bath CP, Dell CP, Hicks CA, Gilmore J, Ambler SJ, Ward MA, Bleakman D. O'Neill MJ, et al. Among authors: gilmore j. Eur J Pharmacol. 1997 Aug 6;332(2):121-31. doi: 10.1016/s0014-2999(97)01074-1. Eur J Pharmacol. 1997. PMID: 9286613

9

PET ligands [¹⁸F]LSN3316612 and [¹¹C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain.

Lu S, Haskali MB, Ruley KM, Dreyfus NJ, DuBois SL, Paul S, Liow JS, Morse CL, Kowalski A, Gladding RL, Gilmore J, Mogg AJ, Morin SM, Lindsay-Scott PJ, Ruble JC, Kant NA, Shcherbinin S, Barth VN, Johnson MP, Cuadrado M, Jambrina E, Mannes AJ, Nuthall HN, Zoghbi SS, Jesudason CD, Innis RB, Pike VW. Lu S, et al. Among authors: gilmore j. Sci Transl Med. 2020 May 13;12(543):eaau2939. doi: 10.1126/scitranslmed.aau2939. Sci Transl Med. 2020. PMID: 32404505 Free PMC article.

10

Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips.

Snyder DW, Cho HL, Gilmore J. Snyder DW, et al. Among authors: gilmore j. Eur J Pharmacol. 1991 Mar 26;195(2):209-15. doi: 10.1016/0014-2999(91)90537-z. Eur J Pharmacol. 1991. PMID: 1651863

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