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Neuropathy target esterase and phospholipid deacylation.
Glynn P. Glynn P. Biochim Biophys Acta. 2005 Sep 15;1736(2):87-93. doi: 10.1016/j.bbalip.2005.08.002. Biochim Biophys Acta. 2005. PMID: 16137924 Review.
Neuropathy target esterase is required for adult vertebrate axon maintenance.
Read DJ, Li Y, Chao MV, Cavanagh JB, Glynn P. Read DJ, et al. Among authors: glynn p. J Neurosci. 2009 Sep 16;29(37):11594-600. doi: 10.1523/JNEUROSCI.3007-09.2009. J Neurosci. 2009. PMID: 19759306 Free PMC article.
Neuronal phospholipid deacylation is essential for axonal and synaptic integrity.
Glynn P. Glynn P. Biochim Biophys Acta. 2013 Mar;1831(3):633-41. doi: 10.1016/j.bbalip.2012.07.023. Epub 2012 Aug 7. Biochim Biophys Acta. 2013. PMID: 22903185 Review.
Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila.
Mühlig-Versen M, da Cruz AB, Tschäpe JA, Moser M, Büttner R, Athenstaedt K, Glynn P, Kretzschmar D. Mühlig-Versen M, et al. Among authors: glynn p. J Neurosci. 2005 Mar 16;25(11):2865-73. doi: 10.1523/JNEUROSCI.5097-04.2005. J Neurosci. 2005. PMID: 15772346 Free PMC article.
Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice.
Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, Buettner R. Moser M, et al. Among authors: glynn p. Mol Cell Biol. 2004 Feb;24(4):1667-79. doi: 10.1128/mcb.24.4.1667-1679.2004. Mol Cell Biol. 2004. PMID: 14749382 Free PMC article.
Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells.
Zaccheo O, Dinsdale D, Meacock PA, Glynn P. Zaccheo O, et al. Among authors: glynn p. J Biol Chem. 2004 Jun 4;279(23):24024-33. doi: 10.1074/jbc.M400830200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044461
Inhibition of neurite outgrowth in differentiating mouse N2a neuroblastoma cells by phenyl saligenin phosphate: effects on MAP kinase (ERK 1/2) activation, neurofilament heavy chain phosphorylation and neuropathy target esterase activity.
Hargreaves AJ, Fowler MJ, Sachana M, Flaskos J, Bountouri M, Coutts IC, Glynn P, Harris W, Graham McLean W. Hargreaves AJ, et al. Among authors: glynn p. Biochem Pharmacol. 2006 Apr 14;71(8):1240-7. doi: 10.1016/j.bcp.2006.01.008. Epub 2006 Feb 24. Biochem Pharmacol. 2006. PMID: 16499876
Phospholipase B activity and organophosphorus compound toxicity in cultured neural cells.
Read DJ, Langford L, Barbour HR, Forshaw PJ, Glynn P. Read DJ, et al. Among authors: glynn p. Toxicol Appl Pharmacol. 2007 Mar;219(2-3):190-5. doi: 10.1016/j.taap.2006.08.002. Epub 2006 Aug 8. Toxicol Appl Pharmacol. 2007. PMID: 16963094
Organophosphates induce distal axonal damage, but not brain oedema, by inactivating neuropathy target esterase.
Read DJ, Li Y, Chao MV, Cavanagh JB, Glynn P. Read DJ, et al. Among authors: glynn p. Toxicol Appl Pharmacol. 2010 May 15;245(1):108-15. doi: 10.1016/j.taap.2010.02.010. Epub 2010 Feb 24. Toxicol Appl Pharmacol. 2010. PMID: 20188121
Axonal degeneration and neuropathy target esterase.
Glynn P. Glynn P. Arh Hig Rada Toksikol. 2007 Sep;58(3):355-8. doi: 10.2478/v10004-007-0029-z. Arh Hig Rada Toksikol. 2007. PMID: 18050888 Review.
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