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Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk.
Es-Haghi M, Godakumara K, Häling A, Lättekivi F, Lavrits A, Viil J, Andronowska A, Nafee T, James V, Jaakma Ü, Salumets A, Fazeli A. Es-Haghi M, et al. Among authors: godakumara k. Cell Commun Signal. 2019 Nov 14;17(1):146. doi: 10.1186/s12964-019-0448-x. Cell Commun Signal. 2019. PMID: 31727082 Free PMC article.
Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers.
Dissanayake K, Nõmm M, Lättekivi F, Ressaissi Y, Godakumara K, Lavrits A, Midekessa G, Viil J, Bæk R, Jørgensen MM, Bhattacharjee S, Andronowska A, Salumets A, Jaakma Ü, Fazeli A. Dissanayake K, et al. Among authors: godakumara k. Theriogenology. 2020 Jun;149:104-116. doi: 10.1016/j.theriogenology.2020.03.008. Epub 2020 Apr 4. Theriogenology. 2020. PMID: 32259747 Free article.
Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication.
Godakumara K, Ord J, Lättekivi F, Dissanayake K, Viil J, Boggavarapu NR, Faridani OR, Jääger K, Velthut-Meikas A, Jaakma Ü, Salumets A, Fazeli A. Godakumara K, et al. Reprod Biol Endocrinol. 2021 Jul 21;19(1):115. doi: 10.1186/s12958-021-00801-5. Reprod Biol Endocrinol. 2021. PMID: 34289864 Free PMC article.
17 results