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Pharmacological HIF-1 stabilization promotes intestinal epithelial healing through regulation of α-integrin expression and function.
Goggins BJ, Minahan K, Sherwin S, Soh WS, Pryor J, Bruce J, Liu G, Mathe A, Knight D, Horvat JC, Walker MM, Keely S. Goggins BJ, et al. Am J Physiol Gastrointest Liver Physiol. 2021 Apr 1;320(4):G420-G438. doi: 10.1152/ajpgi.00192.2020. Epub 2021 Jan 20. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33470153 Free article.
PAI-1 augments mucosal damage in colitis.
Kaiko GE, Chen F, Lai CW, Chiang IL, Perrigoue J, Stojmirović A, Li K, Muegge BD, Jain U, VanDussen KL, Goggins BJ, Keely S, Weaver J, Foster PS, Lawrence DA, Liu TC, Stappenbeck TS. Kaiko GE, et al. Among authors: goggins bj. Sci Transl Med. 2019 Mar 6;11(482):eaat0852. doi: 10.1126/scitranslmed.aat0852. Sci Transl Med. 2019. PMID: 30842312 Free PMC article.
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction.
Fricker M, Goggins BJ, Mateer S, Jones B, Kim RY, Gellatly SL, Jarnicki AG, Powell N, Oliver BG, Radford-Smith G, Talley NJ, Walker MM, Keely S, Hansbro PM. Fricker M, et al. Among authors: goggins bj. JCI Insight. 2018 Feb 8;3(3):e94040. doi: 10.1172/jci.insight.94040. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415878 Free PMC article.
IL-6 Drives Neutrophil-Mediated Pulmonary Inflammation Associated with Bacteremia in Murine Models of Colitis.
Mateer SW, Mathe A, Bruce J, Liu G, Maltby S, Fricker M, Goggins BJ, Tay HL, Marks E, Burns G, Kim RY, Minahan K, Walker MM, Callister RC, Foster PS, Horvat JC, Hansbro PM, Keely S. Mateer SW, et al. Among authors: goggins bj. Am J Pathol. 2018 Jul;188(7):1625-1639. doi: 10.1016/j.ajpath.2018.03.016. Epub 2018 Apr 22. Am J Pathol. 2018. PMID: 29684360 Free article.
Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome.
Liu G, Mateer SW, Hsu A, Goggins BJ, Tay H, Mathe A, Fan K, Neal R, Bruce J, Burns G, Minahan K, Maltby S, Fricker M, Foster PS, Wark PAB, Hansbro PM, Keely S. Liu G, et al. Among authors: goggins bj. Mucosal Immunol. 2019 Jul;12(4):862-873. doi: 10.1038/s41385-019-0163-3. Epub 2019 Apr 11. Mucosal Immunol. 2019. PMID: 30976089 Free article.
14 results