Gogliotti R - Search Results

1

Biophysical characterization of zinc ejection from HIV nucleocapsid protein by anti-HIV 2,2'-dithiobis[benzamides] and benzisothiazolones.

Loo JA, Holler TP, Sanchez J, Gogliotti R, Maloney L, Reily MD. Loo JA, et al. Among authors: gogliotti r. J Med Chem. 1996 Oct 11;39(21):4313-20. doi: 10.1021/jm960253w. J Med Chem. 1996. PMID: 8863808

2

The in vitro ejection of zinc from human immunodeficiency virus (HIV) type 1 nucleocapsid protein by disulfide benzamides with cellular anti-HIV activity.

Tummino PJ, Scholten JD, Harvey PJ, Holler TP, Maloney L, Gogliotti R, Domagala J, Hupe D. Tummino PJ, et al. Among authors: gogliotti r. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):969-73. doi: 10.1073/pnas.93.3.969. Proc Natl Acad Sci U S A. 1996. PMID: 8577770 Free PMC article.

Several disulfide benzamides have been shown to possess wide-spectrum antiretroviral activity in cell culture at low micromolar to submicromolar concentrations, inhibiting human immunodeficiency virus (HIV) type 1 (HIV-1) clinical and drug-resistant strains along with HIV-2 and s …

Several disulfide benzamides have been shown to possess wide-spectrum antiretroviral activity in cell culture at low micromolar to submicrom …

3

The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities.

Tummino PJ, Harvey PJ, McQuade T, Domagala J, Gogliotti R, Sanchez J, Song Y, Hupe D. Tummino PJ, et al. Among authors: gogliotti r. Antimicrob Agents Chemother. 1997 Feb;41(2):394-400. doi: 10.1128/AAC.41.2.394. Antimicrob Agents Chemother. 1997. PMID: 9021197 Free PMC article.

4

2,2'-Dithiobisbenzamides and 2-benzisothiazolones, two new classes of antiretroviral agents: SAR and mechanistic considerations.

Domagala JM, Gogliotti R, Sanchez JP, Stier MA, Musa K, Song Y, Loo J, Reily M, Tummino P, Harvey P, Hupe D, Sharmeen L, Mack D, Scholten J, Saunders J, McQuade T. Domagala JM, et al. Among authors: gogliotti r. Drug Des Discov. 1997 May;15(1):49-61. Drug Des Discov. 1997. PMID: 9332831

5

A new class of anti-HIV-1 agents targeted toward the nucleocapsid protein NCp7: the 2,2'-dithiobisbenzamides.

Domagala JM, Bader JP, Gogliotti RD, Sanchez JP, Stier MA, Song Y, Prasad JV, Tummino PJ, Scholten J, Harvey P, Holler T, Gracheck S, Hupe D, Rice WG, Schultz R. Domagala JM, et al. Among authors: gogliotti rd. Bioorg Med Chem. 1997 Mar;5(3):569-79. doi: 10.1016/s0968-0896(96)00269-6. Bioorg Med Chem. 1997. PMID: 9113335

6

2,2'-Dithiobisbenzamides derived from alpha-, beta- and gamma-amino acids possessing anti-HIV activities: synthesis and structure-activity relationship.

Prasad JV, Loo JA, Boyer FE, Stier MA, Gogliotti RD, Turner WJ, Harvey PJ, Kramer MR, Mack DP, Scholten JD, Gracheck SJ, Domagala JM. Prasad JV, et al. Among authors: gogliotti rd. Bioorg Med Chem. 1998 Oct;6(10):1707-30. doi: 10.1016/s0968-0896(98)00118-7. Bioorg Med Chem. 1998. PMID: 9839002

7

The synthesis, structure-activity, and structure-side effect relationships of a series of 8-alkoxy- and 5-amino-8-alkoxyquinolone antibacterial agents.

Sanchez JP, Gogliotti RD, Domagala JM, Gracheck SJ, Huband MD, Sesnie JA, Cohen MA, Shapiro MA. Sanchez JP, et al. Among authors: gogliotti rd. J Med Chem. 1995 Oct 27;38(22):4478-87. doi: 10.1021/jm00022a013. J Med Chem. 1995. PMID: 7473575

8

New 8-(trifluoromethyl)-substituted quinolones. The benefits of the 8-fluoro group with reduced phototoxic risk.

Sanchez JP, Bridges AJ, Bucsh R, Domagala JM, Gogliotti RD, Hagen SE, Heifetz CL, Joannides ET, Sesnie JC, Shapiro MA, et al. Sanchez JP, et al. Among authors: gogliotti rd. J Med Chem. 1992 Jan 24;35(2):361-7. doi: 10.1021/jm00080a023. J Med Chem. 1992. PMID: 1732554

9

Quinolone antibacterials: preparation and activity of bridged bicyclic analogues of the C7-piperazine.

Kiely JS, Hutt MP, Culbertson TP, Bucsh RA, Worth DF, Lesheski LE, Gogliotti RD, Sesnie JC, Solomon M, Mich TF. Kiely JS, et al. Among authors: gogliotti rd. J Med Chem. 1991 Feb;34(2):656-63. doi: 10.1021/jm00106a029. J Med Chem. 1991. PMID: 1995890

10

High-affinity small-molecule inhibitors of the menin-mixed lineage leukemia (MLL) interaction closely mimic a natural protein-protein interaction.

He S, Senter TJ, Pollock J, Han C, Upadhyay SK, Purohit T, Gogliotti RD, Lindsley CW, Cierpicki T, Stauffer SR, Grembecka J. He S, et al. Among authors: gogliotti rd. J Med Chem. 2014 Feb 27;57(4):1543-56. doi: 10.1021/jm401868d. Epub 2014 Feb 6. J Med Chem. 2014. PMID: 24472025 Free PMC article.

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