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Treatment inferred from mutations identified using massive parallel sequencing leads to clinical benefit in some heavily pretreated cancer patients.
Zick A, Peretz T, Lotem M, Hubert A, Katz D, Temper M, Rottenberg Y, Uziely B, Nechushtan H, Meirovitz A, Sonnenblick A, Sapir E, Edelman D, Goldberg Y, Lossos A, Rosenberg S, Fried I, Finklstein R, Pikarsky E, Goldshmidt H. Zick A, et al. Among authors: goldberg y. Medicine (Baltimore). 2017 May;96(20):e6931. doi: 10.1097/MD.0000000000006931. Medicine (Baltimore). 2017. PMID: 28514312 Free PMC article.
Mutation spectrum in HNPCC in the Israeli population.
Goldberg Y, Porat RM, Kedar I, Shochat C, Sagi M, Eilat A, Mendelson S, Hamburger T, Nissan A, Hubert A, Kadouri L, Pikarski E, Lerer I, Abeliovich D, Bercovich D, Peretz T. Goldberg Y, et al. Fam Cancer. 2008;7(4):309-17. doi: 10.1007/s10689-008-9191-y. Epub 2008 Apr 4. Fam Cancer. 2008. PMID: 18389388
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
Goldberg Y, Porat RM, Kedar I, Shochat C, Galinsky D, Hamburger T, Hubert A, Strul H, Kariiv R, Ben-Avi L, Savion M, Pikarsky E, Abeliovich D, Bercovich D, Lerer I, Peretz T. Goldberg Y, et al. Fam Cancer. 2010 Jun;9(2):141-50. doi: 10.1007/s10689-009-9298-9. Fam Cancer. 2010. PMID: 19851887
Two BRCA1/2 founder mutations in Jews of Sephardic origin.
Sagi M, Eilat A, Ben Avi L, Goldberg Y, Bercovich D, Hamburger T, Peretz T, Lerer I. Sagi M, et al. Among authors: goldberg y. Fam Cancer. 2011 Mar;10(1):59-63. doi: 10.1007/s10689-010-9395-9. Fam Cancer. 2011. PMID: 21063910
Lynch Syndrome in high risk Ashkenazi Jews in Israel.
Goldberg Y, Kedar I, Kariiv R, Halpern N, Plesser M, Hubert A, Kaduri L, Sagi M, Lerer I, Abeliovich D, Hamburger T, Nissan A, Goldshmidt H, Solar I, Geva R, Strul H, Rosner G, Baris H, Levi Z, Peretz T. Goldberg Y, et al. Fam Cancer. 2014 Mar;13(1):65-73. doi: 10.1007/s10689-013-9675-2. Fam Cancer. 2014. PMID: 23990280
331 results