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Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases.
Ghigo A, Perino A, Mehel H, Zahradníková A Jr, Morello F, Leroy J, Nikolaev VO, Damilano F, Cimino J, De Luca E, Richter W, Westenbroek R, Catterall WA, Zhang J, Yan C, Conti M, Gomez AM, Vandecasteele G, Hirsch E, Fischmeister R. Ghigo A, et al. Among authors: gomez am. Circulation. 2012 Oct 23;126(17):2073-83. doi: 10.1161/CIRCULATIONAHA.112.114074. Epub 2012 Sep 24. Circulation. 2012. PMID: 23008439 Free PMC article.
The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes.
Pereira L, Métrich M, Fernández-Velasco M, Lucas A, Leroy J, Perrier R, Morel E, Fischmeister R, Richard S, Bénitah JP, Lezoualc'h F, Gómez AM. Pereira L, et al. Among authors: gomez am. J Physiol. 2007 Sep 1;583(Pt 2):685-94. doi: 10.1113/jphysiol.2007.133066. Epub 2007 Jun 28. J Physiol. 2007. PMID: 17599964 Free PMC article.
Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling.
Gellen B, Fernández-Velasco M, Briec F, Vinet L, LeQuang K, Rouet-Benzineb P, Bénitah JP, Pezet M, Palais G, Pellegrin N, Zhang A, Perrier R, Escoubet B, Marniquet X, Richard S, Jaisser F, Gómez AM, Charpentier F, Mercadier JJ. Gellen B, et al. Among authors: gomez am. Circulation. 2008 Apr 8;117(14):1778-86. doi: 10.1161/CIRCULATIONAHA.107.731893. Epub 2008 Mar 31. Circulation. 2008. PMID: 18378612
Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling.
Loyer X, Gómez AM, Milliez P, Fernandez-Velasco M, Vangheluwe P, Vinet L, Charue D, Vaudin E, Zhang W, Sainte-Marie Y, Robidel E, Marty I, Mayer B, Jaisser F, Mercadier JJ, Richard S, Shah AM, Bénitah JP, Samuel JL, Heymes C. Loyer X, et al. Among authors: gomez am. Circulation. 2008 Jun 24;117(25):3187-98. doi: 10.1161/CIRCULATIONAHA.107.741702. Epub 2008 Jun 9. Circulation. 2008. PMID: 18541744 Free article.
Mineralocorticoid modulation of cardiac ryanodine receptor activity is associated with downregulation of FK506-binding proteins.
Gómez AM, Rueda A, Sainte-Marie Y, Pereira L, Zissimopoulos S, Zhu X, Schaub R, Perrier E, Perrier R, Latouche C, Richard S, Picot MC, Jaisser F, Lai FA, Valdivia HH, Benitah JP. Gómez AM, et al. Circulation. 2009 Apr 28;119(16):2179-87. doi: 10.1161/CIRCULATIONAHA.108.805804. Epub 2009 Apr 13. Circulation. 2009. PMID: 19364981 Free article.
Paradoxical effect of increased diastolic Ca(2+) release and decreased sinoatrial node activity in a mouse model of catecholaminergic polymorphic ventricular tachycardia.
Neco P, Torrente AG, Mesirca P, Zorio E, Liu N, Priori SG, Napolitano C, Richard S, Benitah JP, Mangoni ME, Gómez AM. Neco P, et al. Among authors: gomez am. Circulation. 2012 Jul 24;126(4):392-401. doi: 10.1161/CIRCULATIONAHA.111.075382. Epub 2012 Jun 18. Circulation. 2012. PMID: 22711277 Free PMC article.
Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension.
Hautefort A, Mendes-Ferreira P, Sabourin J, Manaud G, Bertero T, Rucker-Martin C, Riou M, Adão R, Manoury B, Lambert M, Boet A, Lecerf F, Domergue V, Brás-Silva C, Gomez AM, Montani D, Girerd B, Humbert M, Antigny F, Perros F. Hautefort A, et al. Among authors: gomez am. Circulation. 2019 Feb 12;139(7):932-948. doi: 10.1161/CIRCULATIONAHA.118.033744. Circulation. 2019. PMID: 30586714
Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Bartoli F, Bailey MA, Rode B, Mateo P, Antigny F, Bedouet K, Gerbaud P, Gosain R, Plante J, Norman K, Gomez S, Lefebvre F, Rucker-Martin C, Ainscough JFX, Kearney MT, Bruns AF, Shi J, Appleby HL, Young RS, Shawer HM, Debant M, Gomez AM, Beech DJ, Foster R, Benitah JP, Sabourin J. Bartoli F, et al. Among authors: gomez s, gomez am. Circulation. 2020 Jan 21;141(3):199-216. doi: 10.1161/CIRCULATIONAHA.118.038891. Epub 2020 Jan 7. Circulation. 2020. PMID: 31906693 Free PMC article.
Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia.
Fernández-Velasco M, Rueda A, Rizzi N, Benitah JP, Colombi B, Napolitano C, Priori SG, Richard S, Gómez AM. Fernández-Velasco M, et al. Among authors: gomez am. Circ Res. 2009 Jan 30;104(2):201-9, 12p following 209. doi: 10.1161/CIRCRESAHA.108.177493. Epub 2008 Dec 18. Circ Res. 2009. PMID: 19096022 Free PMC article.
460 results