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Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene.
Alexander WS, Viney EM, Zhang JG, Metcalf D, Kauppi M, Hyland CD, Carpinelli MR, Stevenson W, Croker BA, Hilton AA, Ellis S, Selan C, Nandurkar HH, Goodnow CC, Kile BT, Nicola NA, Roberts AW, Hilton DJ. Alexander WS, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16442-7. doi: 10.1073/pnas.0607872103. Epub 2006 Oct 24. Proc Natl Acad Sci U S A. 2006. PMID: 17062753 Free PMC article.
Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity.
Sabouri Z, Schofield P, Horikawa K, Spierings E, Kipling D, Randall KL, Langley D, Roome B, Vazquez-Lombardi R, Rouet R, Hermes J, Chan TD, Brink R, Dunn-Walters DK, Christ D, Goodnow CC. Sabouri Z, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2567-75. doi: 10.1073/pnas.1406974111. Epub 2014 May 12. Proc Natl Acad Sci U S A. 2014. PMID: 24821781 Free PMC article. Clinical Trial.
Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Burnett DL, Schofield P, Langley DB, Jackson J, Bourne K, Wilson E, Porebski BT, Buckle AM, Brink R, Goodnow CC, Christ D. Burnett DL, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2020 Sep 8;117(36):22341-22350. doi: 10.1073/pnas.2005102117. Epub 2020 Aug 27. Proc Natl Acad Sci U S A. 2020. PMID: 32855302 Free PMC article.
Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes.
Enders A, Short A, Miosge LA, Bergmann H, Sontani Y, Bertram EM, Whittle B, Balakishnan B, Yoshida K, Sjollema G, Field MA, Andrews TD, Hagiwara H, Goodnow CC. Enders A, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4513-8. doi: 10.1073/pnas.1402739111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616512 Free PMC article.
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells.
Altin JA, Daley SR, Howitt J, Rickards HJ, Batkin AK, Horikawa K, Prasad SJ, Nelms KA, Kumar S, Wu LC, Tan SS, Cook MC, Goodnow CC. Altin JA, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2067-74. doi: 10.1073/pnas.1322739111. Epub 2014 Jan 13. Proc Natl Acad Sci U S A. 2014. PMID: 24520172 Free PMC article.
Comparison of predicted and actual consequences of missense mutations.
Miosge LA, Field MA, Sontani Y, Cho V, Johnson S, Palkova A, Balakishnan B, Liang R, Zhang Y, Lyon S, Beutler B, Whittle B, Bertram EM, Enders A, Goodnow CC, Andrews TD. Miosge LA, et al. Among authors: goodnow cc. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):E5189-98. doi: 10.1073/pnas.1511585112. Epub 2015 Aug 12. Proc Natl Acad Sci U S A. 2015. PMID: 26269570 Free PMC article.
287 results