Goodson M - Search Results

1

Corepressors: custom tailoring and alterations while you wait.

Goodson M, Jonas BA, Privalsky MA. Goodson M, et al. Nucl Recept Signal. 2005;3:e003. doi: 10.1621/nrs.03003. Epub 2005 Oct 21. Nucl Recept Signal. 2005. PMID: 16604171 Free PMC article.

2

Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing.

Jonas BA, Varlakhanova N, Hayakawa F, Goodson M, Privalsky ML. Jonas BA, et al. Among authors: goodson m. Mol Endocrinol. 2007 Aug;21(8):1924-39. doi: 10.1210/me.2007-0035. Epub 2007 May 22. Mol Endocrinol. 2007. PMID: 17519355 Free PMC article.

3

Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors.

Goodson ML, Jonas BA, Privalsky ML. Goodson ML, et al. J Biol Chem. 2005 Mar 4;280(9):7493-503. doi: 10.1074/jbc.M411514200. Epub 2005 Jan 4. J Biol Chem. 2005. PMID: 15632172 Free PMC article.

4

Alternative mRNA splicing of corepressors generates variants that play opposing roles in adipocyte differentiation.

Goodson ML, Mengeling BJ, Jonas BA, Privalsky ML. Goodson ML, et al. J Biol Chem. 2011 Dec 30;286(52):44988-99. doi: 10.1074/jbc.M111.291625. Epub 2011 Nov 7. J Biol Chem. 2011. PMID: 22065574 Free PMC article.

5

An improved high throughput protein-protein interaction assay for nuclear hormone receptors.

Goodson ML, Farboud B, Privalsky ML. Goodson ML, et al. Nucl Recept Signal. 2007 Mar 9;5:e002. doi: 10.1621/nrs.05002. Nucl Recept Signal. 2007. PMID: 17464356 Free PMC article.

6

Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.

Mengeling BJ, Phan TQ, Goodson ML, Privalsky ML. Mengeling BJ, et al. J Biol Chem. 2011 Feb 11;286(6):4236-47. doi: 10.1074/jbc.M110.200964. Epub 2010 Dec 3. J Biol Chem. 2011. PMID: 21131350 Free PMC article.

7

SMRTε, a corepressor variant, interacts with a restricted subset of nuclear receptors, including the retinoic acid receptors α and β.

Mengeling BJ, Goodson ML, Bourguet W, Privalsky ML. Mengeling BJ, et al. Mol Cell Endocrinol. 2012 Apr 4;351(2):306-16. doi: 10.1016/j.mce.2012.01.006. Epub 2012 Jan 12. Mol Cell Endocrinol. 2012. PMID: 22266197 Free PMC article.

8

Corepressor diversification by alternative mRNA splicing is species specific.

Privalsky ML, Snyder CA, Goodson ML. Privalsky ML, et al. BMC Evol Biol. 2016 Oct 19;16(1):221. doi: 10.1186/s12862-016-0781-2. BMC Evol Biol. 2016. PMID: 27756201 Free PMC article.

9

Alteration of NCoR corepressor splicing in mice causes increased body weight and hepatosteatosis without glucose intolerance.

Goodson ML, Young BM, Snyder CA, Schroeder AC, Privalsky ML. Goodson ML, et al. Mol Cell Biol. 2014 Nov 15;34(22):4104-14. doi: 10.1128/MCB.00554-14. Epub 2014 Sep 2. Mol Cell Biol. 2014. PMID: 25182530 Free PMC article.

10

Specific ablation of the NCoR corepressor δ splice variant reveals alternative RNA splicing as a key regulator of hepatic metabolism.

Goodson ML, Knotts TA, Campbell EL, Snyder CA, Young BM, Privalsky ML. Goodson ML, et al. PLoS One. 2020 Oct 26;15(10):e0241238. doi: 10.1371/journal.pone.0241238. eCollection 2020. PLoS One. 2020. PMID: 33104749 Free PMC article.

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