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Helminth-induced arginase-1 exacerbates lung inflammation and disease severity in tuberculosis.
Monin L, Griffiths KL, Lam WY, Gopal R, Kang DD, Ahmed M, Rajamanickam A, Cruz-Lagunas A, Zúñiga J, Babu S, Kolls JK, Mitreva M, Rosa BA, Ramos-Payan R, Morrison TE, Murray PJ, Rangel-Moreno J, Pearce EJ, Khader SA. Monin L, et al. Among authors: gopal r. J Clin Invest. 2015 Dec;125(12):4699-713. doi: 10.1172/JCI77378. Epub 2015 Nov 16. J Clin Invest. 2015. PMID: 26571397 Free PMC article.
CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.
Slight SR, Rangel-Moreno J, Gopal R, Lin Y, Fallert Junecko BA, Mehra S, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Pavon L, Kaushal D, Reinhart TA, Randall TD, Khader SA. Slight SR, et al. Among authors: gopal r. J Clin Invest. 2013 Feb;123(2):712-26. doi: 10.1172/JCI65728. Epub 2013 Jan 2. J Clin Invest. 2013. PMID: 23281399 Free PMC article.
S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis.
Gopal R, Monin L, Torres D, Slight S, Mehra S, McKenna KC, Fallert Junecko BA, Reinhart TA, Kolls J, Báez-Saldaña R, Cruz-Lagunas A, Rodríguez-Reyna TS, Kumar NP, Tessier P, Roth J, Selman M, Becerril-Villanueva E, Baquera-Heredia J, Cumming B, Kasprowicz VO, Steyn AJ, Babu S, Kaushal D, Zúñiga J, Vogl T, Rangel-Moreno J, Khader SA. Gopal R, et al. Am J Respir Crit Care Med. 2013 Nov 1;188(9):1137-46. doi: 10.1164/rccm.201304-0803OC. Am J Respir Crit Care Med. 2013. PMID: 24047412 Free PMC article.
Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis.
Domingo-Gonzalez R, Das S, Griffiths KL, Ahmed M, Bambouskova M, Gopal R, Gondi S, Muñoz-Torrico M, Salazar-Lezama MA, Cruz-Lagunas A, Jiménez-Álvarez L, Ramirez-Martinez G, Espinosa-Soto R, Sultana T, Lyons-Weiler J, Reinhart TA, Arcos J, de la Luz Garcia-Hernandez M, Mastrangelo MA, Al-Hammadi N, Townsend R, Balada-Llasat JM, Torrelles JB, Kaplan G, Horne W, Kolls JK, Artyomov MN, Rangel-Moreno J, Zúñiga J, Khader SA. Domingo-Gonzalez R, et al. Among authors: gopal r. JCI Insight. 2017 Oct 5;2(19):e92973. doi: 10.1172/jci.insight.92973. JCI Insight. 2017. PMID: 28978810 Free PMC article.
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung.
Khader SA, Guglani L, Rangel-Moreno J, Gopal R, Junecko BA, Fountain JJ, Martino C, Pearl JE, Tighe M, Lin YY, Slight S, Kolls JK, Reinhart TA, Randall TD, Cooper AM. Khader SA, et al. Among authors: gopal r. J Immunol. 2011 Nov 15;187(10):5402-7. doi: 10.4049/jimmunol.1101377. Epub 2011 Oct 14. J Immunol. 2011. PMID: 22003199 Free PMC article.
492 results