Gouda H - Search Results

1

Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity.

Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Inaka K, Tanaka H, Yamada M, Ohta K, Gouda H, Nonaka T, Ogasawara W, Tanaka N. Sakamoto Y, et al. Among authors: gouda h. Sci Rep. 2015 Jun 9;5:11151. doi: 10.1038/srep11151. Sci Rep. 2015. PMID: 26057589 Free PMC article.

2

Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.

Sakamoto Y, Suzuki Y, Nakamura A, Watanabe Y, Sekiya M, Roppongi S, Kushibiki C, Iizuka I, Tani O, Sakashita H, Inaka K, Tanaka H, Yamada M, Ohta K, Honma N, Shida Y, Ogasawara W, Nakanishi-Matsui M, Nonaka T, Gouda H, Tanaka N. Sakamoto Y, et al. Among authors: gouda h. Sci Rep. 2019 Sep 19;9(1):13587. doi: 10.1038/s41598-019-49984-3. Sci Rep. 2019. PMID: 31537874 Free PMC article.

3

Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7.

Nakamura A, Suzuki Y, Sakamoto Y, Roppongi S, Kushibiki C, Yonezawa N, Takahashi M, Shida Y, Gouda H, Nonaka T, Tanaka N, Ogasawara W. Nakamura A, et al. Among authors: gouda h. Sci Rep. 2021 Apr 12;11(1):7929. doi: 10.1038/s41598-021-86965-x. Sci Rep. 2021. PMID: 33846449 Free PMC article.

4

Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis.

Sakamoto Y, Suzuki Y, Iizuka I, Tateoka C, Roppongi S, Fujimoto M, Gouda H, Nonaka T, Ogasawara W, Tanaka N. Sakamoto Y, et al. Among authors: gouda h. Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):206-10. doi: 10.1107/S2053230X15000424. Epub 2015 Jan 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 25664797 Free PMC article.

5

Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase.

Kusakabe Y, Ishihara M, Umeda T, Kuroda D, Nakanishi M, Kitade Y, Gouda H, Nakamura KT, Tanaka N. Kusakabe Y, et al. Among authors: gouda h. Sci Rep. 2015 Nov 17;5:16641. doi: 10.1038/srep16641. Sci Rep. 2015. PMID: 26573329 Free PMC article.

6

Formal Syntheses of (-)-Lepadiformines A, C, and (-)-Fasicularin.

Takashima K, Hayakawa D, Gouda H, Toyooka N. Takashima K, et al. Among authors: gouda h. J Org Chem. 2019 May 3;84(9):5222-5229. doi: 10.1021/acs.joc.9b00071. Epub 2019 Apr 15. J Org Chem. 2019. PMID: 30943035

7

A molecular interaction field describing nonconventional intermolecular interactions and its application to protein-ligand interaction prediction.

Hayakawa D, Sawada N, Watanabe Y, Gouda H. Hayakawa D, et al. Among authors: gouda h. J Mol Graph Model. 2020 May;96:107515. doi: 10.1016/j.jmgm.2019.107515. Epub 2019 Dec 23. J Mol Graph Model. 2020. PMID: 31896525 Free article.

8

Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists.

Nagahara T, Saitoh T, Kutsumura N, Irukayama-Tomobe Y, Ogawa Y, Kuroda D, Gouda H, Kumagai H, Fujii H, Yanagisawa M, Nagase H. Nagahara T, et al. Among authors: gouda h. J Med Chem. 2015 Oct 22;58(20):7931-7. doi: 10.1021/acs.jmedchem.5b00988. Epub 2015 Aug 26. J Med Chem. 2015. PMID: 26267383

9

A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome.

Watanabe H, Watanabe Y, Tashiro Y, Mushiroda T, Ozeki T, Hashizume H, Sueki H, Yamamoto T, Utsunomiya-Tate N, Gouda H, Kusakabe Y. Watanabe H, et al. Among authors: gouda h. J Dermatol Sci. 2017 Dec;88(3):320-329. doi: 10.1016/j.jdermsci.2017.08.007. Epub 2017 Aug 24. J Dermatol Sci. 2017. PMID: 28870516

10

Design and Synthesis of Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton and Their Pharmacologies.

Nagase H, Yamamoto N, Yata M, Ohrui S, Okada T, Saitoh T, Kutsumura N, Nagumo Y, Irukayama-Tomobe Y, Ishikawa Y, Ogawa Y, Hirayama S, Kuroda D, Watanabe Y, Gouda H, Yanagisawa M. Nagase H, et al. Among authors: gouda h. J Med Chem. 2017 Feb 9;60(3):1018-1040. doi: 10.1021/acs.jmedchem.6b01418. Epub 2017 Jan 18. J Med Chem. 2017. PMID: 28051300

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