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Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer.
Naulaerts S, Datsi A, Borras DM, Antoranz Martinez A, Messiaen J, Vanmeerbeek I, Sprooten J, Laureano RS, Govaerts J, Panovska D, Derweduwe M, Sabel MC, Rapp M, Ni W, Mackay S, Van Herck Y, Gelens L, Venken T, More S, Bechter O, Bergers G, Liston A, De Vleeschouwer S, Van Den Eynde BJ, Lambrechts D, Verfaillie M, Bosisio F, Tejpar S, Borst J, Sorg RV, De Smet F, Garg AD. Naulaerts S, et al. Among authors: govaerts j. Sci Transl Med. 2023 Apr 12;15(691):eadd1016. doi: 10.1126/scitranslmed.add1016. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043555
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer.
Laureano RS, Sprooten J, Vanmeerbeerk I, Borras DM, Govaerts J, Naulaerts S, Berneman ZN, Beuselinck B, Bol KF, Borst J, Coosemans A, Datsi A, Fučíková J, Kinget L, Neyns B, Schreibelt G, Smits E, Sorg RV, Spisek R, Thielemans K, Tuyaerts S, De Vleeschouwer S, de Vries IJM, Xiao Y, Garg AD. Laureano RS, et al. Among authors: govaerts j. Oncoimmunology. 2022 Jul 4;11(1):2096363. doi: 10.1080/2162402X.2022.2096363. eCollection 2022. Oncoimmunology. 2022. PMID: 35800158 Free PMC article.
Trial watch: chemotherapy-induced immunogenic cell death in oncology.
Sprooten J, Laureano RS, Vanmeerbeek I, Govaerts J, Naulaerts S, Borras DM, Kinget L, Fucíková J, Špíšek R, Jelínková LP, Kepp O, Kroemer G, Krysko DV, Coosemans A, Vaes RDW, De Ruysscher D, De Vleeschouwer S, Wauters E, Smits E, Tejpar S, Beuselinck B, Hatse S, Wildiers H, Clement PM, Vandenabeele P, Zitvogel L, Garg AD. Sprooten J, et al. Among authors: govaerts j. Oncoimmunology. 2023 Jun 3;12(1):2219591. doi: 10.1080/2162402X.2023.2219591. eCollection 2023. Oncoimmunology. 2023. PMID: 37284695 Free PMC article. Review.
Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer.
Borràs DM, Verbandt S, Ausserhofer M, Sturm G, Lim J, Verge GA, Vanmeerbeek I, Laureano RS, Govaerts J, Sprooten J, Hong Y, Wall R, De Hertogh G, Sagaert X, Bislenghi G, D'Hoore A, Wolthuis A, Finotello F, Park WY, Naulaerts S, Tejpar S, Garg AD. Borràs DM, et al. Among authors: govaerts j. Cell Discov. 2023 Nov 15;9(1):114. doi: 10.1038/s41421-023-00605-4. Cell Discov. 2023. PMID: 37968259 Free PMC article.
Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells.
Sprooten J, Vanmeerbeek I, Datsi A, Govaerts J, Naulaerts S, Laureano RS, Borràs DM, Calvet A, Malviya V, Kuballa M, Felsberg J, Sabel MC, Rapp M, Knobbe-Thomsen C, Liu P, Zhao L, Kepp O, Boon L, Tejpar S, Borst J, Kroemer G, Schlenner S, De Vleeschouwer S, Sorg RV, Garg AD. Sprooten J, et al. Among authors: govaerts j. Cell Rep Med. 2024 Jan 16;5(1):101377. doi: 10.1016/j.xcrm.2023.101377. Cell Rep Med. 2024. PMID: 38232703 Free PMC article.
Use of hare bone for the manufacture of a Clovis bead.
Surovell TA, Litynski ML, Allaun SA, Buckley M, Schoborg TA, Govaerts JA, O'Brien MJ, Pelton SR, Sanders PH, Mackie ME, Kelly RL. Surovell TA, et al. Among authors: govaerts ja. Sci Rep. 2024 Feb 5;14(1):2937. doi: 10.1038/s41598-024-53390-9. Sci Rep. 2024. PMID: 38316967 Free PMC article.
Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model.
Van Breedam E, Buyle-Huybrecht T, Govaerts J, Meysman P, Bours A, Boeren M, Di Stefano J, Caers T, De Reu H, Dirkx L, Schippers J, Bartholomeus E, Lebrun M, Sadzot-Delvaux C, Rybakowska P, Alarcón-Riquelme ME, Marañón C, Laukens K, Delputte P, Ogunjimi B, Ponsaerts P. Van Breedam E, et al. Among authors: govaerts j. Front Immunol. 2023 May 23;14:1177245. doi: 10.3389/fimmu.2023.1177245. eCollection 2023. Front Immunol. 2023. PMID: 37287975 Free PMC article.
177 results