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The natural compound silvestrol is a potent inhibitor of Ebola virus replication.
Biedenkopf N, Lange-Grünweller K, Schulte FW, Weißer A, Müller C, Becker D, Becker S, Hartmann RK, Grünweller A. Biedenkopf N, et al. Among authors: grunweller a. Antiviral Res. 2017 Jan;137:76-81. doi: 10.1016/j.antiviral.2016.11.011. Epub 2016 Nov 15. Antiviral Res. 2017. PMID: 27864075
Inhibition of Zika Virus Replication by Silvestrol.
Elgner F, Sabino C, Basic M, Ploen D, Grünweller A, Hildt E. Elgner F, et al. Among authors: grunweller a. Viruses. 2018 Mar 27;10(4):149. doi: 10.3390/v10040149. Viruses. 2018. PMID: 29584632 Free PMC article.
Silvestrol Inhibits Chikungunya Virus Replication.
Henss L, Scholz T, Grünweller A, Schnierle BS. Henss L, et al. Among authors: grunweller a. Viruses. 2018 Oct 30;10(11):592. doi: 10.3390/v10110592. Viruses. 2018. PMID: 30380742 Free PMC article.
Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.
Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oestereich L, Elgner F, Glitscher M, Hildt E, Singh K, Wendel HG, Hartmann RK, Ziebuhr J, Grünweller A. Müller C, et al. Among authors: grunweller a. Antiviral Res. 2020 Mar;175:104706. doi: 10.1016/j.antiviral.2020.104706. Epub 2020 Jan 10. Antiviral Res. 2020. PMID: 31931103 Free PMC article.
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