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Phagosomal signalling of the C-type lectin receptor Dectin-1 is terminated by intramembrane proteolysis.
Mentrup T, Stumpff-Niggemann AY, Leinung N, Schlosser C, Schubert K, Wehner R, Tunger A, Schatz V, Neubert P, Gradtke AC, Wolf J, Rose-John S, Saftig P, Dalpke A, Jantsch J, Schmitz M, Fluhrer R, Jacobsen ID, Schröder B. Mentrup T, et al. Among authors: gradtke ac. Nat Commun. 2022 Apr 6;13(1):1880. doi: 10.1038/s41467-022-29474-3. Nat Commun. 2022. PMID: 35388002 Free PMC article.
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
Mentrup T, Theodorou K, Cabrera-Cabrera F, Helbig AO, Happ K, Gijbels M, Gradtke AC, Rabe B, Fukumori A, Steiner H, Tholey A, Fluhrer R, Donners M, Schröder B. Mentrup T, et al. Among authors: gradtke ac. J Exp Med. 2019 Apr 1;216(4):807-830. doi: 10.1084/jem.20171438. Epub 2019 Feb 28. J Exp Med. 2019. PMID: 30819724 Free PMC article.
Mast cells acquire MHCII from dendritic cells during skin inflammation.
Dudeck J, Medyukhina A, Fröbel J, Svensson CM, Kotrba J, Gerlach M, Gradtke AC, Schröder B, Speier S, Figge MT, Dudeck A. Dudeck J, et al. Among authors: gradtke ac. J Exp Med. 2017 Dec 4;214(12):3791-3811. doi: 10.1084/jem.20160783. Epub 2017 Oct 30. J Exp Med. 2017. PMID: 29084819 Free PMC article.