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732 results

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Safety, tolerability, and antibody response of active Aβ immunotherapy with CAD106 in patients with Alzheimer's disease: randomised, double-blind, placebo-controlled, first-in-human study.
Winblad B, Andreasen N, Minthon L, Floesser A, Imbert G, Dumortier T, Maguire RP, Blennow K, Lundmark J, Staufenbiel M, Orgogozo JM, Graf A. Winblad B, et al. Among authors: graf a. Lancet Neurol. 2012 Jul;11(7):597-604. doi: 10.1016/S1474-4422(12)70140-0. Epub 2012 Jun 6. Lancet Neurol. 2012. PMID: 22677258 Clinical Trial.
Active immunotherapy options for Alzheimer's disease.
Winblad B, Graf A, Riviere ME, Andreasen N, Ryan JM. Winblad B, et al. Among authors: graf a. Alzheimers Res Ther. 2014 Jan 30;6(1):7. doi: 10.1186/alzrt237. eCollection 2014. Alzheimers Res Ther. 2014. PMID: 24476230 Free PMC article. Review.
Active Aβ immunotherapy CAD106 in Alzheimer's disease: A phase 2b study.
Vandenberghe R, Riviere ME, Caputo A, Sovago J, Maguire RP, Farlow M, Marotta G, Sanchez-Valle R, Scheltens P, Ryan JM, Graf A. Vandenberghe R, et al. Among authors: graf a. Alzheimers Dement (N Y). 2016 Dec 23;3(1):10-22. doi: 10.1016/j.trci.2016.12.003. eCollection 2017 Jan. Alzheimers Dement (N Y). 2016. PMID: 29067316 Free PMC article.
The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Neumann U, Ufer M, Jacobson LH, Rouzade-Dominguez ML, Huledal G, Kolly C, Lüönd RM, Machauer R, Veenstra SJ, Hurth K, Rueeger H, Tintelnot-Blomley M, Staufenbiel M, Shimshek DR, Perrot L, Frieauff W, Dubost V, Schiller H, Vogg B, Beltz K, Avrameas A, Kretz S, Pezous N, Rondeau JM, Beckmann N, Hartmann A, Vormfelde S, David OJ, Galli B, Ramos R, Graf A, Lopez Lopez C. Neumann U, et al. Among authors: graf a. EMBO Mol Med. 2018 Nov;10(11):e9316. doi: 10.15252/emmm.201809316. EMBO Mol Med. 2018. PMID: 30224383 Free PMC article. Clinical Trial.
A 24-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and tolerability of the rivastigmine patch in Japanese patients with Alzheimer's disease.
Nakamura Y, Imai Y, Shigeta M, Graf A, Shirahase T, Kim H, Fujii A, Mori J, Homma A. Nakamura Y, et al. Among authors: graf a. Dement Geriatr Cogn Dis Extra. 2011 Jan;1(1):163-79. doi: 10.1159/000328929. Epub 2011 Jun 24. Dement Geriatr Cogn Dis Extra. 2011. PMID: 22163242 Free PMC article.
Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE ε4 homozygotes.
Riviere ME, Langbaum JB, Turner RS, Rinne JO, Sui Y, Cazorla P, Ricart J, Meneses K, Caputo A, Tariot PN, Reiman EM, Graf A. Riviere ME, et al. Among authors: graf a. Alzheimers Dement. 2024 Mar;20(3):1839-1850. doi: 10.1002/alz.13532. Epub 2023 Dec 25. Alzheimers Dement. 2024. PMID: 38145469 Free PMC article.
Measuring cognition and function in the preclinical stage of Alzheimer's disease.
Weintraub S, Carrillo MC, Farias ST, Goldberg TE, Hendrix JA, Jaeger J, Knopman DS, Langbaum JB, Park DC, Ropacki MT, Sikkes SAM, Welsh-Bohmer KA, Bain LJ, Brashear R, Budur K, Graf A, Martenyi F, Storck MS, Randolph C. Weintraub S, et al. Among authors: graf a. Alzheimers Dement (N Y). 2018 Feb 13;4:64-75. doi: 10.1016/j.trci.2018.01.003. eCollection 2018. Alzheimers Dement (N Y). 2018. PMID: 29955653 Free PMC article. Review.
732 results