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craig aders
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Graig Aders
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Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment.
Genome Med. 2016 Mar 3;8(1):26. doi: 10.1186/s13073-016-0279-y.
Genome Med. 2016.
PMID: 26939581
Free PMC article.
Mutations acquired during infection were over-represented in transcriptional regulators, notably pmrAB and adeRS, which can mediate resistance to the last line therapies colistin and tigecycline, respectively, as well as transporters, surface structures, and iron acquisiti …
Mutations acquired during infection were over-represented in transcriptional regulators, notably pmrAB and adeRS, which can mediate r …
Transcriptome Remodeling of Acinetobacter baumannii during Infection and Treatment.
Wright MS, Jacobs MR, Bonomo RA, Adams MD.
Wright MS, et al.
mBio. 2017 Mar 7;8(2):e02193-16. doi: 10.1128/mBio.02193-16.
mBio. 2017.
PMID: 28270585
Free PMC article.
Multiple patients had isolates with differential gene expression patterns related to mutations in the pmrAB and adeRS two-component regulatory system genes, as well as significant differences in genes related to antibiotic resistance, iron acquisition, amino acid metabolis …
Multiple patients had isolates with differential gene expression patterns related to mutations in the pmrAB and adeRS two-component r …
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