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Showing results for craig aders
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Genome dynamics of multidrug-resistant Acinetobacter baumannii during infection and treatment.
Wright MS, Iovleva A, Jacobs MR, Bonomo RA, Adams MD. Wright MS, et al. Genome Med. 2016 Mar 3;8(1):26. doi: 10.1186/s13073-016-0279-y. Genome Med. 2016. PMID: 26939581 Free PMC article.
Mutations acquired during infection were over-represented in transcriptional regulators, notably pmrAB and adeRS, which can mediate resistance to the last line therapies colistin and tigecycline, respectively, as well as transporters, surface structures, and iron acquisiti …
Mutations acquired during infection were over-represented in transcriptional regulators, notably pmrAB and adeRS, which can mediate r …
Transcriptome Remodeling of Acinetobacter baumannii during Infection and Treatment.
Wright MS, Jacobs MR, Bonomo RA, Adams MD. Wright MS, et al. mBio. 2017 Mar 7;8(2):e02193-16. doi: 10.1128/mBio.02193-16. mBio. 2017. PMID: 28270585 Free PMC article.
Multiple patients had isolates with differential gene expression patterns related to mutations in the pmrAB and adeRS two-component regulatory system genes, as well as significant differences in genes related to antibiotic resistance, iron acquisition, amino acid metabolis …
Multiple patients had isolates with differential gene expression patterns related to mutations in the pmrAB and adeRS two-component r …