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18 results
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Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.
von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: granda bw. Drug Metab Dispos. 2001 Aug;29(8):1102-9. Drug Metab Dispos. 2001. PMID: 11454728
Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice.
von Moltke LL, Granda BW, Grassi JM, Perloff MD, Vishnuvardhan D, Greenblatt DJ. von Moltke LL, et al. Among authors: granda bw. Drug Metab Dispos. 2004 Aug;32(8):800-4. doi: 10.1124/dmd.32.8.800. Drug Metab Dispos. 2004. PMID: 15258104
Short-term exposure to low-dose ritonavir impairs clearance and enhances adverse effects of trazodone.
Greenblatt DJ, von Moltke LL, Harmatz JS, Fogelman SM, Chen G, Graf JA, Mertzanis P, Byron S, Culm KE, Granda BW, Daily JP, Shader RI. Greenblatt DJ, et al. Among authors: granda bw. J Clin Pharmacol. 2003 Apr;43(4):414-22. doi: 10.1177/0091270003251864. J Clin Pharmacol. 2003. PMID: 12723462 Clinical Trial.
In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat.
Kotegawa T, Laurijssens BE, Von Moltke LL, Cotreau MM, Perloff MD, Venkatakrishnan K, Warrington JS, Granda BW, Harmatz JS, Greenblatt DJ. Kotegawa T, et al. Among authors: granda bw. J Pharmacol Exp Ther. 2002 Sep;302(3):1228-37. doi: 10.1124/jpet.102.035972. J Pharmacol Exp Ther. 2002. PMID: 12183684
Microsomal protein concentration modifies the apparent inhibitory potency of CYP3A inhibitors.
Tran TH, Von Moltke LL, Venkatakrishnan K, Granda BW, Gibbs MA, Obach RS, Harmatz JS, Greenblatt DJ. Tran TH, et al. Among authors: granda bw. Drug Metab Dispos. 2002 Dec;30(12):1441-5. doi: 10.1124/dmd.30.12.1441. Drug Metab Dispos. 2002. PMID: 12433817
Inhibition of human cytochrome P450 isoforms in vitro by zafirlukast.
Shader RI, Granda BW, von Moltke LL, Giancarlo GM, Greenblatt DJ. Shader RI, et al. Among authors: granda bw. Biopharm Drug Dispos. 1999 Nov;20(8):385-8. doi: 10.1002/1099-081x(199911)20:8<385::aid-bdd203>3.0.co;2-7. Biopharm Drug Dispos. 1999. PMID: 10870095
In vitro metabolism of trazodone by CYP3A: inhibition by ketoconazole and human immunodeficiency viral protease inhibitors.
Zalma A, von Moltke LL, Granda BW, Harmatz JS, Shader RI, Greenblatt DJ. Zalma A, et al. Among authors: granda bw. Biol Psychiatry. 2000 Apr 1;47(7):655-61. doi: 10.1016/s0006-3223(99)00176-6. Biol Psychiatry. 2000. PMID: 10745059
Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects.
von Moltke LL, Greenblatt DJ, Grassi JM, Granda BW, Venkatakrishnan K, Duan SX, Fogelman SM, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: granda bw. Biol Psychiatry. 1999 Sep 15;46(6):839-49. doi: 10.1016/s0006-3223(98)00353-9. Biol Psychiatry. 1999. PMID: 10494454
Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.
von Moltke LL, Greenblatt DJ, Granda BW, Grassi JM, Schmider J, Harmatz JS, Shader RI. von Moltke LL, et al. Among authors: granda bw. Psychopharmacology (Berl). 1999 Jul;145(1):113-22. doi: 10.1007/s002130051039. Psychopharmacology (Berl). 1999. PMID: 10445380
Zolpidem metabolism in vitro: responsible cytochromes, chemical inhibitors, and in vivo correlations.
Von Moltke LL, Greenblatt DJ, Granda BW, Duan SX, Grassi JM, Venkatakrishnan K, Harmatz JS, Shader RI. Von Moltke LL, et al. Among authors: granda bw. Br J Clin Pharmacol. 1999 Jul;48(1):89-97. doi: 10.1046/j.1365-2125.1999.00953.x. Br J Clin Pharmacol. 1999. PMID: 10383565 Free PMC article.
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