Grandal I - Search Results

1

B cell acute lymphoblastic leukemia cells mediate RANK-RANKL-dependent bone destruction.

Rajakumar SA, Papp E, Lee KK, Grandal I, Merico D, Liu CC, Allo B, Zhang L, Grynpas MD, Minden MD, Hitzler JK, Guidos CJ, Danska JS. Rajakumar SA, et al. Among authors: grandal i. Sci Transl Med. 2020 Sep 16;12(561):eaba5942. doi: 10.1126/scitranslmed.aba5942. Sci Transl Med. 2020. PMID: 32938796

2

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS. Perova T, et al. Among authors: grandal i. Sci Transl Med. 2014 May 14;6(236):236ra62. doi: 10.1126/scitranslmed.3008661. Sci Transl Med. 2014. PMID: 24828076

3

Targeted blockade of immune mechanisms inhibit B precursor acute lymphoblastic leukemia cell invasion of the central nervous system.

Rajakumar SA, Grandal I, Minden MD, Hitzler JK, Guidos CJ, Danska JS. Rajakumar SA, et al. Among authors: grandal i. Cell Rep Med. 2021 Dec 21;2(12):100470. doi: 10.1016/j.xcrm.2021.100470. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028611 Free PMC article.

4

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS. Gladdy RA, et al. Among authors: grandal i. Cancer Cell. 2003 Jan;3(1):37-50. doi: 10.1016/s1535-6108(02)00236-2. Cancer Cell. 2003. PMID: 12559174 Free article.

5

Johnson RM, Papp E, Grandal I, Kowalski PE, Nutter L, Wong RC, Joseph-George AM, Danska JS, Guidos CJ. Johnson RM, et al. Among authors: grandal i. Genes Dev. 2014 Jun 1;28(11):1179-90. doi: 10.1101/gad.240820.114. Genes Dev. 2014. PMID: 24888589 Free PMC article.

6

Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs.

Dobson SM, García-Prat L, Vanner RJ, Wintersinger J, Waanders E, Gu Z, McLeod J, Gan OI, Grandal I, Payne-Turner D, Edmonson MN, Ma X, Fan Y, Voisin V, Chan-Seng-Yue M, Xie SZ, Hosseini M, Abelson S, Gupta P, Rusch M, Shao Y, Olsen SR, Neale G, Chan SM, Bader G, Easton J, Guidos CJ, Danska JS, Zhang J, Minden MD, Morris Q, Mullighan CG, Dick JE. Dobson SM, et al. Among authors: grandal i. Cancer Discov. 2020 Apr;10(4):568-587. doi: 10.1158/2159-8290.CD-19-1059. Epub 2020 Feb 21. Cancer Discov. 2020. PMID: 32086311 Free PMC article.

7

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Vanner RJ, Dobson SM, Gan OI, McLeod J, Schoof EM, Grandal I, Wintersinger JA, Garcia-Prat L, Hosseini M, Xie SZ, Jin L, Mbong N, Voisin V, Chan-Seng-Yue M, Kennedy JA, Waanders E, Morris Q, Porse B, Chan SM, Guidos CJ, Danska JS, Minden MD, Mullighan CG, Dick JE. Vanner RJ, et al. Among authors: grandal i. Blood Cancer Discov. 2022 Jan;3(1):16-31. doi: 10.1158/2643-3230.BCD-20-0216. Epub 2021 Oct 11. Blood Cancer Discov. 2022. PMID: 35019858 Free PMC article.

8

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

Guidos CJ, Williams CJ, Grandal I, Knowles G, Huang MT, Danska JS. Guidos CJ, et al. Among authors: grandal i. Genes Dev. 1996 Aug 15;10(16):2038-54. doi: 10.1101/gad.10.16.2038. Genes Dev. 1996. PMID: 8769647 Free article.

9

Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.

Williams CJ, Grandal I, Vesprini DJ, Wojtyra U, Danska JS, Guidos CJ. Williams CJ, et al. Among authors: grandal i. Mol Cell Biol. 2001 Jan;21(2):400-13. doi: 10.1128/MCB.21.2.400-413.2001. Mol Cell Biol. 2001. PMID: 11134329 Free PMC article.

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