Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 1
1990 2
1991 2
1993 3
1994 2
1995 2
1997 3
1998 3
1999 1
2000 2
2001 2
2002 1
2003 1
2005 2
2006 3
2007 2
2008 2
2009 6
2010 4
2011 11
2012 6
2013 3
2014 6
2015 6
2016 4
2017 5
2019 2
2020 4
2021 4
2022 1
2023 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

93 results

Results by year

Filters applied: . Clear all
Page 1
Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer's Disease.
Brisendine MH, Nichenko AS, Bandara AB, Willoughby OS, Amiri N, Weingrad Z, Specht KS, Bond JM, Addington A, Jones RG 3rd, Murach KA, Poelzing S, Craige SM, Grange RW, Drake JC. Brisendine MH, et al. Among authors: grange rw. Function (Oxf). 2023 Dec 4;5(1):zqad066. doi: 10.1093/function/zqad066. eCollection 2024. Function (Oxf). 2023. PMID: 38111538 Free PMC article.
Exercise promotes muscle, mitochondria, and cognitive health and is proposed to be a potential therapeutic for AD, but no study has investigated how skeletal muscle adapts to exercise training in an AD-like context. ...Changes in peripheral systems, specifically neu …
Exercise promotes muscle, mitochondria, and cognitive health and is proposed to be a potential therapeutic for AD, but no study has i …
Prolonged voluntary wheel running reveals unique adaptations in mdx mice treated with microdystrophin constructs ± the nNOS-binding site.
Hamm SE, Yuan C, McQueen LF, Wallace MA, Zhang H, Arora A, Garafalo AM, McMillan RP, Lawlor MW, Prom MJ, Ott EM, Yan J, Addington AK, Morris CA, Gonzalez JP, Grange RW. Hamm SE, et al. Among authors: grange rw. Front Physiol. 2023 Jun 26;14:1166206. doi: 10.3389/fphys.2023.1166206. eCollection 2023. Front Physiol. 2023. PMID: 37435312 Free PMC article.
We tested the effects of prolonged voluntary wheel running on the muscle function of mdx mice treated with one of two different microdystrophin constructs. ...Robust expression of microdystrophin occurred in diaphragm, quadriceps, and heart muscles of all treated mi …
We tested the effects of prolonged voluntary wheel running on the muscle function of mdx mice treated with one of two different micro …
Erratum: Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice.
Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW. Hamm SE, et al. Among authors: grange rw. Mol Ther Methods Clin Dev. 2021 Nov 5;23:460. doi: 10.1016/j.omtm.2021.10.005. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34820472 Free PMC article.
Voluntary wheel running complements microdystrophin gene therapy to improve muscle function in mdx mice.
Hamm SE, Fathalikhani DD, Bukovec KE, Addington AK, Zhang H, Perry JB, McMillan RP, Lawlor MW, Prom MJ, Vanden Avond MA, Kumar SN, Coleman KE, Dupont JB, Mack DL, Brown DA, Morris CA, Gonzalez JP, Grange RW. Hamm SE, et al. Among authors: grange rw. Mol Ther Methods Clin Dev. 2021 Mar 3;21:144-160. doi: 10.1016/j.omtm.2021.02.024. eCollection 2021 Jun 11. Mol Ther Methods Clin Dev. 2021. PMID: 33850950 Free PMC article.
Robust expression of microdystrophin occurred in heart and limb muscles of treated mice. mdxRGT versus mdxGT mice showed increased microdystrophin in quadriceps but decreased levels in diaphragm. mdx final treadmill fatigue time was depressed compared to all groups, improv …
Robust expression of microdystrophin occurred in heart and limb muscles of treated mice. mdxRGT versus mdxGT mice showed increased mi …
A novel murine muscle loading model to investigate Achilles musculotendinous adaptation.
Rezvani SN, Nichols AEC, Grange RW, Dahlgren LA, Brolinson PG, Wang VM. Rezvani SN, et al. Among authors: grange rw. J Appl Physiol (1985). 2021 Apr 1;130(4):1043-1051. doi: 10.1152/japplphysiol.00638.2020. Epub 2021 Feb 11. J Appl Physiol (1985). 2021. PMID: 33571057 Free PMC article.
Here, we introduce a novel mouse model of hindlimb muscle loading designed to achieve a tissue-targeted therapeutic exercise. ...Our model facilitates the future investigation of mechanisms whereby rehabilitative muscle loading promotes healing of Achilles tendon in …
Here, we introduce a novel mouse model of hindlimb muscle loading designed to achieve a tissue-targeted therapeutic exercise. ...Our …
Potential cross-talk between muscle and tendon in Duchenne muscular dystrophy.
Yuan C, Arora A, Garofalo AM, Grange RW. Yuan C, et al. Among authors: grange rw. Connect Tissue Res. 2021 Jan;62(1):40-52. doi: 10.1080/03008207.2020.1810247. Epub 2020 Aug 31. Connect Tissue Res. 2021. PMID: 32867551
PURPOSE: To describe potential signaling (cross-talk) between dystrophic skeletal muscle and tendon in Duchenne muscular dystrophy. MATERIALS AND METHODS: Review of Duchenne muscular dystrophy and associated literature relevant to muscle-tendon cross-talk. RESULTS A …
PURPOSE: To describe potential signaling (cross-talk) between dystrophic skeletal muscle and tendon in Duchenne muscular dystrophy. M …
A novel ex vivo protocol to mimic human walking gait: implications for Duchenne muscular dystrophy.
Bukovec KE, Hu X, Borkowski M, Jeffery D, Blemker SS, Grange RW. Bukovec KE, et al. Among authors: grange rw. J Appl Physiol (1985). 2020 Oct 1;129(4):779-791. doi: 10.1152/japplphysiol.00002.2020. Epub 2020 Sep 3. J Appl Physiol (1985). 2020. PMID: 32881620 Free PMC article.
We developed a novel ex vivo mouse protocol to mimic in vivo human soleus muscle function predicted by musculoskeletal simulations to better understand eccentric contractions during gait and ultimately to better understand their effects in Duchenne muscular dystrophy (DMD) …
We developed a novel ex vivo mouse protocol to mimic in vivo human soleus muscle function predicted by musculoskeletal simulations to …
Laminin-111 protein therapy after disease onset slows muscle disease in a mouse model of laminin-alpha2 related congenital muscular dystrophy.
Barraza-Flores P, Bukovec KE, Dagda M, Conner BW, Oliveira-Santos A, Grange RW, Burkin DJ. Barraza-Flores P, et al. Among authors: grange rw. Hum Mol Genet. 2020 Aug 3;29(13):2162-2170. doi: 10.1093/hmg/ddaa104. Hum Mol Genet. 2020. PMID: 32472139 Free PMC article.
Laminin-alpha2 related congenital muscular dystrophy (LAMA2-CMD) is a fatal muscle disease caused by mutations in the LAMA2 gene. Laminin-alpha2 is critical for the formation of laminin-211 and -221 heterotrimers in the muscle basal lamina. ...In this study, we test …
Laminin-alpha2 related congenital muscular dystrophy (LAMA2-CMD) is a fatal muscle disease caused by mutations in the LAMA2 gene. Lam …
AAV-Mediated Gene Transfer Restores a Normal Muscle Transcriptome in a Canine Model of X-Linked Myotubular Myopathy.
Dupont JB, Guo J, Renaud-Gabardos E, Poulard K, Latournerie V, Lawlor MW, Grange RW, Gray JT, Buj-Bello A, Childers MK, Mack DL. Dupont JB, et al. Among authors: grange rw. Mol Ther. 2020 Feb 5;28(2):382-393. doi: 10.1016/j.ymthe.2019.10.018. Epub 2019 Nov 11. Mol Ther. 2020. PMID: 31784415 Free PMC article.
Our previous work on a canine model of XLMTM showed that a single rAAV8-cMTM1 systemic infusion corrected structural abnormalities within the muscle and restored contractile function, with affected dogs surviving more than 4 years post injection. This remarkable therapeuti …
Our previous work on a canine model of XLMTM showed that a single rAAV8-cMTM1 systemic infusion corrected structural abnormalities within th …
93 results