Gray DHD - Search Results

1

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice.

Jain R, Sheridan JM, Policheni A, Heinlein M, Gandolfo LC, Dewson G, Smyth GK, Sansom SN, Fu NY, Visvader JE, Holländer GA, Strasser A, Gray DHD. Jain R, et al. Among authors: gray dhd. Blood. 2017 Dec 7;130(23):2504-2515. doi: 10.1182/blood-2017-03-771576. Epub 2017 Sep 29. Blood. 2017. PMID: 28972012 Free PMC article.

2

Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim.

Liston A, Lesage S, Gray DH, O'Reilly LA, Strasser A, Fahrer AM, Boyd RL, Wilson J, Baxter AG, Gallo EM, Crabtree GR, Peng K, Wilson SR, Goodnow CC. Liston A, et al. Immunity. 2004 Dec;21(6):817-30. doi: 10.1016/j.immuni.2004.10.014. Immunity. 2004. PMID: 15589170 Free article.

3

Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration.

Alpdogan O, Hubbard VM, Smith OM, Patel N, Lu S, Goldberg GL, Gray DH, Feinman J, Kochman AA, Eng JM, Suh D, Muriglan SJ, Boyd RL, van den Brink MR. Alpdogan O, et al. Blood. 2006 Mar 15;107(6):2453-60. doi: 10.1182/blood-2005-07-2831. Epub 2005 Nov 22. Blood. 2006. PMID: 16304055 Free PMC article.

4

Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.

Gray DH, Seach N, Ueno T, Milton MK, Liston A, Lew AM, Goodnow CC, Boyd RL. Gray DH, et al. Blood. 2006 Dec 1;108(12):3777-85. doi: 10.1182/blood-2006-02-004531. Epub 2006 Aug 8. Blood. 2006. PMID: 16896157 Free article.

5

XIAP discriminates between type I and type II FAS-induced apoptosis.

Jost PJ, Grabow S, Gray D, McKenzie MD, Nachbur U, Huang DC, Bouillet P, Thomas HE, Borner C, Silke J, Strasser A, Kaufmann T. Jost PJ, et al. Nature. 2009 Aug 20;460(7258):1035-9. doi: 10.1038/nature08229. Epub 2009 Jul 22. Nature. 2009. PMID: 19626005 Free PMC article.

6

Defects in the Bcl-2-regulated apoptotic pathway lead to preferential increase of CD25 low Foxp3+ anergic CD4+ T cells.

Zhan Y, Zhang Y, Gray D, Carrington EM, Bouillet P, Ko HJ, O'Reilly L, Wicks IP, Strasser A, Lew AM. Zhan Y, et al. J Immunol. 2011 Aug 15;187(4):1566-77. doi: 10.4049/jimmunol.1100027. Epub 2011 Jul 8. J Immunol. 2011. PMID: 21742968 Free PMC article.

7

The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor.

Papadopoulou AS, Dooley J, Linterman MA, Pierson W, Ucar O, Kyewski B, Zuklys S, Hollander GA, Matthys P, Gray DH, De Strooper B, Liston A. Papadopoulou AS, et al. Nat Immunol. 2011 Dec 18;13(2):181-7. doi: 10.1038/ni.2193. Nat Immunol. 2011. PMID: 22179202 Free PMC article.

8

Elevated Mcl-1 inhibits thymocyte apoptosis and alters thymic selection.

Campbell KJ, Gray DH, Anstee N, Strasser A, Cory S. Campbell KJ, et al. Cell Death Differ. 2012 Dec;19(12):1962-71. doi: 10.1038/cdd.2012.84. Epub 2012 Jun 29. Cell Death Differ. 2012. PMID: 22743995 Free PMC article.

9

The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.

Gray DH, Kupresanin F, Berzins SP, Herold MJ, O'Reilly LA, Bouillet P, Strasser A. Gray DH, et al. Immunity. 2012 Sep 21;37(3):451-62. doi: 10.1016/j.immuni.2012.05.030. Epub 2012 Sep 6. Immunity. 2012. PMID: 22960223 Free PMC article.

10

Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.

Mason KD, Lin A, Robb L, Josefsson EC, Henley KJ, Gray DH, Kile BT, Roberts AW, Strasser A, Huang DC, Waring P, O'Reilly LA. Mason KD, et al. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2599-604. doi: 10.1073/pnas.1215097110. Epub 2013 Jan 24. Proc Natl Acad Sci U S A. 2013. PMID: 23349374 Free PMC article.

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