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The Genomics of Colorectal Cancer in Populations with African and European Ancestry.
Myer PA, Lee JK, Madison RW, Pradhan K, Newberg JY, Isasi CR, Klempner SJ, Frampton GM, Ross JS, Venstrom JM, Schrock AB, Das S, Augenlicht L, Verma A, Greally JM, Raj SM, Goel S, Ali SM. Myer PA, et al. Among authors: greally jm. Cancer Discov. 2022 May 2;12(5):1282-1293. doi: 10.1158/2159-8290.CD-21-0813. Cancer Discov. 2022. PMID: 35176763 Free PMC article.
Aberrant DNA methylation in malignant melanoma.
Schinke C, Mo Y, Yu Y, Amiri K, Sosman J, Greally J, Verma A. Schinke C, et al. Melanoma Res. 2010 Aug;20(4):253-65. doi: 10.1097/CMR.0b013e328338a35a. Melanoma Res. 2010. PMID: 20418788 Free PMC article. Review.
Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms.
Nischal S, Bhattacharyya S, Christopeit M, Yu Y, Zhou L, Bhagat TD, Sohal D, Will B, Mo Y, Suzuki M, Pardanani A, McDevitt M, Maciejewski JP, Melnick AM, Greally JM, Steidl U, Moliterno A, Verma A. Nischal S, et al. Among authors: greally jm. Cancer Res. 2013 Feb 1;73(3):1076-85. doi: 10.1158/0008-5472.CAN-12-0735. Epub 2012 Oct 11. Cancer Res. 2013. PMID: 23066032 Free PMC article.
Kidney cancer is characterized by aberrant methylation of tissue-specific enhancers that are prognostic for overall survival.
Hu CY, Mohtat D, Yu Y, Ko YA, Shenoy N, Bhattacharya S, Izquierdo MC, Park AS, Giricz O, Vallumsetla N, Gundabolu K, Ware K, Bhagat TD, Suzuki M, Pullman J, Liu XS, Greally JM, Susztak K, Verma A. Hu CY, et al. Among authors: greally jm. Clin Cancer Res. 2014 Aug 15;20(16):4349-60. doi: 10.1158/1078-0432.CCR-14-0494. Epub 2014 Jun 10. Clin Cancer Res. 2014. PMID: 24916699 Free PMC article.
Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.
Bhagat TD, Zou Y, Huang S, Park J, Palmer MB, Hu C, Li W, Shenoy N, Giricz O, Choudhary G, Yu Y, Ko YA, Izquierdo MC, Park AS, Vallumsetla N, Laurence R, Lopez R, Suzuki M, Pullman J, Kaner J, Gartrell B, Hakimi AA, Greally JM, Patel B, Benhadji K, Pradhan K, Verma A, Susztak K. Bhagat TD, et al. Among authors: greally jm. J Biol Chem. 2017 Jan 20;292(3):837-846. doi: 10.1074/jbc.M116.745208. Epub 2016 Dec 1. J Biol Chem. 2017. PMID: 27909050 Free PMC article.
Epigenetically Aberrant Stroma in MDS Propagates Disease via Wnt/β-Catenin Activation.
Bhagat TD, Chen S, Bartenstein M, Barlowe AT, Von Ahrens D, Choudhary GS, Tivnan P, Amin E, Marcondes AM, Sanders MA, Hoogenboezem RM, Kambhampati S, Ramachandra N, Mantzaris I, Sukrithan V, Laurence R, Lopez R, Bhagat P, Giricz O, Sohal D, Wickrema A, Yeung C, Gritsman K, Aplan P, Hochedlinger K, Yu Y, Pradhan K, Zhang J, Greally JM, Mukherjee S, Pellagatti A, Boultwood J, Will B, Steidl U, Raaijmakers MHGP, Deeg HJ, Kharas MG, Verma A. Bhagat TD, et al. Among authors: greally jm. Cancer Res. 2017 Sep 15;77(18):4846-4857. doi: 10.1158/0008-5472.CAN-17-0282. Epub 2017 Jul 6. Cancer Res. 2017. PMID: 28684528 Free PMC article.
Altered hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways.
Bhattacharyya S, Pradhan K, Campbell N, Mazdo J, Vasantkumar A, Maqbool S, Bhagat TD, Gupta S, Suzuki M, Yu Y, Greally JM, Steidl U, Bradner J, Dawlaty M, Godley L, Maitra A, Verma A. Bhattacharyya S, et al. Among authors: greally jm. Genome Res. 2017 Nov;27(11):1830-1842. doi: 10.1101/gr.222794.117. Epub 2017 Oct 6. Genome Res. 2017. PMID: 28986391 Free PMC article.
213 results