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A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.
Griffiths SJ, Koegl M, Boutell C, Zenner HL, Crump CM, Pica F, Gonzalez O, Friedel CC, Barry G, Martin K, Craigon MH, Chen R, Kaza LN, Fossum E, Fazakerley JK, Efstathiou S, Volpi A, Zimmer R, Ghazal P, Haas J. Griffiths SJ, et al. PLoS Pathog. 2013;9(8):e1003514. doi: 10.1371/journal.ppat.1003514. Epub 2013 Aug 8. PLoS Pathog. 2013. PMID: 23950709 Free PMC article.
VZV Replication Assays.
Griffiths SJ, Haas J. Griffiths SJ, et al. Bio Protoc. 2014 Aug 20;4(16):e1210. doi: 10.21769/BioProtoc.1210. Bio Protoc. 2014. PMID: 29085851 Free PMC article.
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.
Blanc M, Hsieh WY, Robertson KA, Kropp KA, Forster T, Shui G, Lacaze P, Watterson S, Griffiths SJ, Spann NJ, Meljon A, Talbot S, Krishnan K, Covey DF, Wenk MR, Craigon M, Ruzsics Z, Haas J, Angulo A, Griffiths WJ, Glass CK, Wang Y, Ghazal P. Blanc M, et al. Among authors: griffiths wj, griffiths sj. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27. Immunity. 2013. PMID: 23273843 Free PMC article.
Stratified infection medicine: a call to arms.
Russell CD, Griffiths SJ, Baillie JK, Haas J. Russell CD, et al. Among authors: griffiths sj. Lancet Infect Dis. 2014 Jun;14(6):451. doi: 10.1016/S1473-3099(14)70774-1. Lancet Infect Dis. 2014. PMID: 24849724 No abstract available.
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.
Robertson KA, Hsieh WY, Forster T, Blanc M, Lu H, Crick PJ, Yutuc E, Watterson S, Martin K, Griffiths SJ, Enright AJ, Yamamoto M, Pradeepa MM, Lennox KA, Behlke MA, Talbot S, Haas J, Dölken L, Griffiths WJ, Wang Y, Angulo A, Ghazal P. Robertson KA, et al. Among authors: griffiths sj. PLoS Biol. 2016 Mar 3;14(3):e1002364. doi: 10.1371/journal.pbio.1002364. eCollection 2016 Mar. PLoS Biol. 2016. PMID: 26938778 Free PMC article.
39 results