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58 results

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Page 1
Inflammatory Factor IL1alpha Induces Aberrant Astrocyte Proliferation in Spinal Cord Injury Through the Grin2c/Ca(2+)/CaMK2b Pathway.
Xia Y, Ding L, Zhang C, Xu Q, Shi M, Gao T, Zhou FQ, Deng DYB. Xia Y, et al. Neurosci Bull. 2024 Apr;40(4):421-438. doi: 10.1007/s12264-023-01128-4. Epub 2023 Oct 21. Neurosci Bull. 2024. PMID: 37864744 Free PMC article.
Our bioinformatic analysis indicated that Grin2c and Ca(2+) transport functions were inhibited in astrocytes after SCI. ...Blockade of IL1alpha using neutralizing antibody resulted in increased Grin2c expression and the inhibition of astrocyte proliferation post-SCI …
Our bioinformatic analysis indicated that Grin2c and Ca(2+) transport functions were inhibited in astrocytes after SCI. ...Blockade o …
Assessment of NMDA receptor genes (GRIN2A, GRIN2B and GRIN2C) as candidate genes in the development of degenerative lumbar scoliosis.
Kim KT, Kim J, Han YJ, Kim JH, Lee JS, Chung JH. Kim KT, et al. Exp Ther Med. 2013 Mar;5(3):977-981. doi: 10.3892/etm.2013.910. Epub 2013 Jan 21. Exp Ther Med. 2013. PMID: 23408766 Free PMC article.
When the patients were divided into two groups according to clinical characteristics based on Cobb's angle (<20 or 20) and lateral listhesis (<6 mm or 6 mm), associations were observed between rs689730 of GRIN2C and Cobb's angle (codominant, P=0.038; dominant, P=0.02 …
When the patients were divided into two groups according to clinical characteristics based on Cobb's angle (<20 or 20) and lateral listhe …
Change in the gene expression of the N-methyl-D-aspartate receptor 2C subunit by dietary β-naphthoflavone, indole-3-carbinol, or acetaminophen in the rat liver.
Nemoto K, Ikeda A, Tanaka T, Inoue K, Yoshida M, Nishikawa A, Gamou T, Habano W, Ozawa S, Degawa M. Nemoto K, et al. J Toxicol Sci. 2013;38(4):611-7. doi: 10.2131/jts.38.611. J Toxicol Sci. 2013. PMID: 23824016 Free article.
We have previously demonstrated super-induced expression of the Grin2c gene encoding the N-methyl-D-aspartate receptor 2C subunit during the process of liver enlargement induced by phenobarbital, clofibrate, piperonyl butoxide, or lead nitrate. ...Especially, either the 4- …
We have previously demonstrated super-induced expression of the Grin2c gene encoding the N-methyl-D-aspartate receptor 2C subunit dur …
Induced expression of hepatic N-methyl-D-aspartate receptor 2C subunit gene during liver enlargement induced by lead nitrate, a hepatocellular mitogen.
Nemoto K, Ikeda A, Hikida T, Kojima M, Degawa M. Nemoto K, et al. J Toxicol Sci. 2013 Feb;38(1):127-9. doi: 10.2131/jts.38.127. J Toxicol Sci. 2013. PMID: 23358146 Free article.
In the present study, we assessed whether or not Grin2c gene expression was induced during the development of chemically induced liver enlargement with hyperplasia. ...The present findings suggest that the increase in the level of hepatic Grin2c mRNA relates to deve …
In the present study, we assessed whether or not Grin2c gene expression was induced during the development of chemically induced live …
The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons.
Wijayatunge R, Liu F, Shpargel KB, Wayne NJ, Chan U, Boua JV, Magnuson T, West AE. Wijayatunge R, et al. Mol Cell Neurosci. 2018 Mar;87:4-17. doi: 10.1016/j.mcn.2017.11.005. Epub 2017 Dec 15. Mol Cell Neurosci. 2018. PMID: 29254825 Free PMC article. Review.
Loss of Kdm6b also impaired the ability of Brain-Derived Neurotrophic Factor (BDNF) to induce expression of Grin2c and Tiam1 in maturing CGNs. Taken together, these data reveal a previously unknown role for Kdm6b in the postmitotic stages of CGN maturation and suggest that …
Loss of Kdm6b also impaired the ability of Brain-Derived Neurotrophic Factor (BDNF) to induce expression of Grin2c and Tiam1 in matur …
Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia.
Tarabeux J, Kebir O, Gauthier J, Hamdan FF, Xiong L, Piton A, Spiegelman D, Henrion É, Millet B; S2D team; Fathalli F, Joober R, Rapoport JL, DeLisi LE, Fombonne É, Mottron L, Forget-Dubois N, Boivin M, Michaud JL, Drapeau P, Lafrenière RG, Rouleau GA, Krebs MO. Tarabeux J, et al. Transl Psychiatry. 2011 Nov 15;1(11):e55. doi: 10.1038/tp.2011.52. Transl Psychiatry. 2011. PMID: 22833210 Free PMC article.
Here, we identified two de novo mutations in patients with sporadic SCZ in GRIN2A and one de novo mutation in GRIN2B in a patient with ASD. Truncating mutations in GRIN2C, GRIN3A and GRIN3B were identified in both subjects and controls, but no truncating mutations were fou …
Here, we identified two de novo mutations in patients with sporadic SCZ in GRIN2A and one de novo mutation in GRIN2B in a patient with ASD. …
Differential DNA methylation in recovery from shift work disorder.
Lahtinen A, Häkkinen A, Puttonen S, Vanttola P, Viitasalo K, Porkka-Heiskanen T, Härmä M, Paunio T. Lahtinen A, et al. Sci Rep. 2021 Feb 3;11(1):2895. doi: 10.1038/s41598-021-82627-0. Sci Rep. 2021. PMID: 33536559 Free PMC article.
Furthermore, three DMPs from this pathway, corresponding to GRIN2C, CREB1, and CAMK2B, correlated with the degree of recovery (P(unadj) < 0.05). ...
Furthermore, three DMPs from this pathway, corresponding to GRIN2C, CREB1, and CAMK2B, correlated with the degree of recovery (P(unad …
58 results