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UV1 telomerase vaccine with ipilimumab and nivolumab as second line treatment for pleural mesothelioma - A phase II randomised trial.
Haakensen VD, Öjlert ÅK, Thunold S, Farooqi S, Nowak AK, Chin WL, Grundberg O, Szejniuk WM, Cedres S, Sørensen JB, Dalen TS, Lund-Iversen M, Bjaanæs M, Helland Å. Haakensen VD, et al. Among authors: grundberg o. Eur J Cancer. 2024 May;202:113973. doi: 10.1016/j.ejca.2024.113973. Epub 2024 Mar 1. Eur J Cancer. 2024. PMID: 38447379 Free article. Clinical Trial.
Plasma RNA profiling unveils transcriptional signatures associated with resistance to osimertinib in EGFR T790M positive non-small cell lung cancer patients.
Alexeyenko A, Brustugun OT, Eide IJZ, Gencheva R, Kosibaty Z, Lai Y, de Petris L, Tsakonas G, Grundberg O, Franzen B, Viktorsson K, Lewensohn R, Hydbring P, Ekman S. Alexeyenko A, et al. Among authors: grundberg o. Transl Lung Cancer Res. 2022 Oct;11(10):2064-2078. doi: 10.21037/tlcr-22-236. Transl Lung Cancer Res. 2022. PMID: 36386450 Free PMC article.
Ras-Related Protein Rab-32 and Thrombospondin 1 Confer Resistance to the EGFR Tyrosine Kinase Inhibitor Osimertinib by Activating Focal Adhesion Kinase in Non-Small Cell Lung Cancer.
Kosibaty Z, Brustugun OT, Zwicky Eide IJ, Tsakonas G, Grundberg O, De Petris L, McGowan M, Hydbring P, Ekman S. Kosibaty Z, et al. Among authors: grundberg o. Cancers (Basel). 2022 Jul 14;14(14):3430. doi: 10.3390/cancers14143430. Cancers (Basel). 2022. PMID: 35884490 Free PMC article.
Elevated expression of miR-494-3p is associated with resistance to osimertinib in EGFR T790M-positive non-small cell lung cancer.
Kaźmierczak D, Eide IJZ, Gencheva R, Lai Y, Lewensohn R, Tsakonas G, Grundberg O, de Petris L, McGowan M, Brustugun OT, Ekman S, Hydbring P. Kaźmierczak D, et al. Among authors: grundberg o. Transl Lung Cancer Res. 2022 May;11(5):722-734. doi: 10.21037/tlcr-21-955. Transl Lung Cancer Res. 2022. PMID: 35693293 Free PMC article.
NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma.
Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å. Haakensen VD, et al. Among authors: grundberg o. J Transl Med. 2021 May 31;19(1):232. doi: 10.1186/s12967-021-02905-3. J Transl Med. 2021. PMID: 34059094 Free PMC article. Clinical Trial.
Clinicopathological significance of the expression of PD-L1 in non-small cell lung cancer.
Montero MA, Aricak O, Kis L, Yoshikawa A, De Petris L, Grundberg O, Pham HHN, Roden AC, Fukuoka J, Attanoos R, Guijarro R, Alarcón F, Lindström K, Ortiz-Villalón C. Montero MA, et al. Among authors: grundberg o. Ann Diagn Pathol. 2021 Apr;51:151701. doi: 10.1016/j.anndiagpath.2021.151701. Epub 2021 Jan 9. Ann Diagn Pathol. 2021. PMID: 33485052
Capmatinib in MET Exon 14-Mutated or MET-Amplified Non-Small-Cell Lung Cancer.
Wolf J, Seto T, Han JY, Reguart N, Garon EB, Groen HJM, Tan DSW, Hida T, de Jonge M, Orlov SV, Smit EF, Souquet PJ, Vansteenkiste J, Hochmair M, Felip E, Nishio M, Thomas M, Ohashi K, Toyozawa R, Overbeck TR, de Marinis F, Kim TM, Laack E, Robeva A, Le Mouhaer S, Waldron-Lynch M, Sankaran B, Balbin OA, Cui X, Giovannini M, Akimov M, Heist RS; GEOMETRY mono-1 Investigators. Wolf J, et al. N Engl J Med. 2020 Sep 3;383(10):944-957. doi: 10.1056/NEJMoa2002787. N Engl J Med. 2020. PMID: 32877583 Clinical Trial.