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441 results

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GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.
Jewell JL, Fu V, Hong AW, Yu FX, Meng D, Melick CH, Wang H, Lam WM, Yuan HX, Taylor SS, Guan KL. Jewell JL, et al. Among authors: guan kl. Elife. 2019 May 21;8:e43038. doi: 10.7554/eLife.43038. Elife. 2019. PMID: 31112131 Free PMC article.
Regulation of mTORC1 by the Rab and Arf GTPases.
Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, Guan KL. Li L, et al. Among authors: guan kl. J Biol Chem. 2010 Jun 25;285(26):19705-9. doi: 10.1074/jbc.C110.102483. Epub 2010 May 10. J Biol Chem. 2010. PMID: 20457610 Free PMC article.
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.
Zhang D, Contu R, Latronico MV, Zhang J, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, Chen J, Sonenberg N, Condorelli G. Zhang D, et al. Among authors: guan kl. J Clin Invest. 2010 Aug;120(8):2805-16. doi: 10.1172/JCI43008. Epub 2010 Jul 19. J Clin Invest. 2010. PMID: 20644257 Free PMC article.
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling.
Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, Fu XD, Mills GB, Guan KL. Yu FX, et al. Among authors: guan kl. Cell. 2012 Aug 17;150(4):780-91. doi: 10.1016/j.cell.2012.06.037. Epub 2012 Aug 2. Cell. 2012. PMID: 22863277 Free PMC article.
Upstream regulators of the Hippo pathway.
Yu FX, Mo JS, Guan KL. Yu FX, et al. Among authors: guan kl. Cell Cycle. 2012 Nov 15;11(22):4097-8. doi: 10.4161/cc.22322. Epub 2012 Oct 17. Cell Cycle. 2012. PMID: 23075495 Free PMC article. No abstract available.
Amino acid signalling upstream of mTOR.
Jewell JL, Russell RC, Guan KL. Jewell JL, et al. Among authors: guan kl. Nat Rev Mol Cell Biol. 2013 Mar;14(3):133-9. doi: 10.1038/nrm3522. Epub 2013 Jan 30. Nat Rev Mol Cell Biol. 2013. PMID: 23361334 Free PMC article. Review.
Nutrient sensing, metabolism, and cell growth control.
Yuan HX, Xiong Y, Guan KL. Yuan HX, et al. Among authors: guan kl. Mol Cell. 2013 Feb 7;49(3):379-87. doi: 10.1016/j.molcel.2013.01.019. Mol Cell. 2013. PMID: 23395268 Free PMC article. Review.
441 results