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NAD+ and sirtuins in aging and disease.
Imai S, Guarente L. Imai S, et al. Among authors: guarente l. Trends Cell Biol. 2014 Aug;24(8):464-71. doi: 10.1016/j.tcb.2014.04.002. Epub 2014 Apr 29. Trends Cell Biol. 2014. PMID: 24786309 Free PMC article. Review.
The brain, sirtuins, and ageing.
Satoh A, Imai SI, Guarente L. Satoh A, et al. Among authors: guarente l. Nat Rev Neurosci. 2017 May 18;18(6):362-374. doi: 10.1038/nrn.2017.42. Nat Rev Neurosci. 2017. PMID: 28515492 Review.
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. Vaziri H, et al. Among authors: guarente l. Cell. 2001 Oct 19;107(2):149-59. doi: 10.1016/s0092-8674(01)00527-x. Cell. 2001. PMID: 11672523 Free article.
Dietary restriction: standing up for sirtuins.
Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E. Baur JA, et al. Among authors: guarente lp. Science. 2010 Aug 27;329(5995):1012-3; author reply 1013-4. doi: 10.1126/science.329.5995.1012. Science. 2010. PMID: 20798296 Free PMC article. No abstract available.
Aging and disease: connections to sirtuins.
Donmez G, Guarente L. Donmez G, et al. Among authors: guarente l. Aging Cell. 2010 Apr;9(2):285-90. doi: 10.1111/j.1474-9726.2010.00548.x. Aging Cell. 2010. PMID: 20409078 Free article. Review.
302 results