Guimaraes JC - Search Results

1

Evaluation of 244,000 synthetic sequences reveals design principles to optimize translation in Escherichia coli.

Cambray G, Guimaraes JC, Arkin AP. Cambray G, et al. Among authors: guimaraes jc. Nat Biotechnol. 2018 Nov;36(10):1005-1015. doi: 10.1038/nbt.4238. Epub 2018 Sep 24. Nat Biotechnol. 2018. PMID: 30247489

2

Rationally designed families of orthogonal RNA regulators of translation.

Mutalik VK, Qi L, Guimaraes JC, Lucks JB, Arkin AP. Mutalik VK, et al. Among authors: guimaraes jc. Nat Chem Biol. 2012 Mar 25;8(5):447-54. doi: 10.1038/nchembio.919. Nat Chem Biol. 2012. PMID: 22446835

3

Precise and reliable gene expression via standard transcription and translation initiation elements.

Mutalik VK, Guimaraes JC, Cambray G, Lam C, Christoffersen MJ, Mai QA, Tran AB, Paull M, Keasling JD, Arkin AP, Endy D. Mutalik VK, et al. Among authors: guimaraes jc. Nat Methods. 2013 Apr;10(4):354-60. doi: 10.1038/nmeth.2404. Epub 2013 Mar 10. Nat Methods. 2013. PMID: 23474465

4

D-Tailor: automated analysis and design of DNA sequences.

Guimaraes JC, Rocha M, Arkin AP, Cambray G. Guimaraes JC, et al. Bioinformatics. 2014 Apr 15;30(8):1087-1094. doi: 10.1093/bioinformatics/btt742. Epub 2014 Jan 6. Bioinformatics. 2014. PMID: 24398007 Free PMC article.

5

Transcript level and sequence determinants of protein abundance and noise in Escherichia coli.

Guimaraes JC, Rocha M, Arkin AP. Guimaraes JC, et al. Nucleic Acids Res. 2014 Apr;42(8):4791-9. doi: 10.1093/nar/gku126. Epub 2014 Feb 7. Nucleic Acids Res. 2014. PMID: 24510099 Free PMC article.

6

Quantitative estimation of activity and quality for collections of functional genetic elements.

Mutalik VK, Guimaraes JC, Cambray G, Mai QA, Christoffersen MJ, Martin L, Yu A, Lam C, Rodriguez C, Bennett G, Keasling JD, Endy D, Arkin AP. Mutalik VK, et al. Among authors: guimaraes jc. Nat Methods. 2013 Apr;10(4):347-53. doi: 10.1038/nmeth.2403. Epub 2013 Mar 10. Nat Methods. 2013. PMID: 23474467

7

Measurement and modeling of intrinsic transcription terminators.

Cambray G, Guimaraes JC, Mutalik VK, Lam C, Mai QA, Thimmaiah T, Carothers JM, Arkin AP, Endy D. Cambray G, et al. Among authors: guimaraes jc. Nucleic Acids Res. 2016 Aug 19;44(14):7006. doi: 10.1093/nar/gkw379. Epub 2016 Apr 29. Nucleic Acids Res. 2016. PMID: 27131373 Free PMC article. No abstract available.

8

Measurement and modeling of intrinsic transcription terminators.

Cambray G, Guimaraes JC, Mutalik VK, Lam C, Mai QA, Thimmaiah T, Carothers JM, Arkin AP, Endy D. Cambray G, et al. Among authors: guimaraes jc. Nucleic Acids Res. 2013 May;41(9):5139-48. doi: 10.1093/nar/gkt163. Epub 2013 Mar 19. Nucleic Acids Res. 2013. PMID: 23511967 Free PMC article.

9

Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.

Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Essig K, et al. Among authors: guimaraes jc. Nat Commun. 2018 Sep 19;9(1):3810. doi: 10.1038/s41467-018-06184-3. Nat Commun. 2018. PMID: 30232334 Free PMC article.

10

The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan.

Mittal N, Guimaraes JC, Gross T, Schmidt A, Vina-Vilaseca A, Nedialkova DD, Aeschimann F, Leidel SA, Spang A, Zavolan M. Mittal N, et al. Among authors: guimaraes jc. Nat Commun. 2017 Sep 6;8(1):457. doi: 10.1038/s41467-017-00539-y. Nat Commun. 2017. PMID: 28878244 Free PMC article.

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