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Major β cell-specific functions of NKX2.2 are mediated via the NK2-specific domain.
Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L. Abarinov V, et al. Among authors: guney ma. Genes Dev. 2023 Jun 1;37(11-12):490-504. doi: 10.1101/gad.350569.123. Epub 2023 Jun 26. Genes Dev. 2023. PMID: 37364986 Free PMC article.
Pancreatic β cell regeneration: To β or not to β.
Guney MA, Lorberbaum DS, Sussel L. Guney MA, et al. Curr Opin Physiol. 2020 Apr;14:13-20. doi: 10.1016/j.cophys.2019.10.019. Epub 2019 Nov 5. Curr Opin Physiol. 2020. PMID: 32864533 Free PMC article.
Pancreas cell fate.
Guney MA, Gannon M. Guney MA, et al. Birth Defects Res C Embryo Today. 2009 Sep;87(3):232-48. doi: 10.1002/bdrc.20156. Birth Defects Res C Embryo Today. 2009. PMID: 19750517 Free PMC article. Review.
Connective tissue growth factor (CTGF) inactivation leads to defects in islet cell lineage allocation and beta-cell proliferation during embryogenesis.
Crawford LA, Guney MA, Oh YA, Deyoung RA, Valenzuela DM, Murphy AJ, Yancopoulos GD, Lyons KM, Brigstock DR, Economides A, Gannon M. Crawford LA, et al. Among authors: guney ma. Mol Endocrinol. 2009 Mar;23(3):324-36. doi: 10.1210/me.2008-0045. Epub 2009 Jan 8. Mol Endocrinol. 2009. PMID: 19131512 Free PMC article.
OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.
Ahdritz G, Bouatta N, Floristean C, Kadyan S, Xia Q, Gerecke W, O'Donnell TJ, Berenberg D, Fisk I, Zanichelli N, Zhang B, Nowaczynski A, Wang B, Stepniewska-Dziubinska MM, Zhang S, Ojewole A, Guney ME, Biderman S, Watkins AM, Ra S, Lorenzo PR, Nivon L, Weitzner B, Ban YA, Chen S, Zhang M, Li C, Song SL, He Y, Sorger PK, Mostaque E, Zhang Z, Bonneau R, AlQuraishi M. Ahdritz G, et al. Among authors: guney me. Nat Methods. 2024 May 14. doi: 10.1038/s41592-024-02272-z. Online ahead of print. Nat Methods. 2024. PMID: 38744917
164 results