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Targeted inactivation of the mecB gene, encoding cystathionine-gamma-lyase, shows that the reverse transsulfuration pathway is required for high-level cephalosporin biosynthesis in Acremonium chrysogenum C10 but not for methionine induction of the cephalosporin genes.
Liu G, Casqueiro J, Bañuelos O, Cardoza RE, Gutiérrez S, Martín JF. Liu G, et al. Among authors: gutierrez s. J Bacteriol. 2001 Mar;183(5):1765-72. doi: 10.1128/JB.183.5.1765-1772.2001. J Bacteriol. 2001. PMID: 11160109 Free PMC article.
Silencing of the aspergillopepsin B (pepB) gene of Aspergillus awamori by antisense RNA expression or protease removal by gene disruption results in a large increase in thaumatin production.
Moralejo FJ, Cardoza RE, Gutierrez S, Lombraña M, Fierro F, Martín JF. Moralejo FJ, et al. Among authors: gutierrez s. Appl Environ Microbiol. 2002 Jul;68(7):3550-9. doi: 10.1128/AEM.68.7.3550-3559.2002. Appl Environ Microbiol. 2002. PMID: 12089041 Free PMC article.
811 results