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LHON gene therapy vector prevents visual loss and optic neuropathy induced by G11778A mutant mitochondrial DNA: biodistribution and toxicology profile.
Koilkonda R, Yu H, Talla V, Porciatti V, Feuer WJ, Hauswirth WW, Chiodo V, Erger KE, Boye SL, Lewin AS, Conlon TJ, Renner L, Neuringer M, Detrisac C, Guy J. Koilkonda R, et al. Among authors: guy j. Invest Ophthalmol Vis Sci. 2014 Oct 23;55(12):7739-53. doi: 10.1167/iovs.14-15388. Invest Ophthalmol Vis Sci. 2014. PMID: 25342621 Free PMC article.
Gene Therapy for Leber Hereditary Optic Neuropathy: Initial Results.
Feuer WJ, Schiffman JC, Davis JL, Porciatti V, Gonzalez P, Koilkonda RD, Yuan H, Lalwani A, Lam BL, Guy J. Feuer WJ, et al. Among authors: guy j. Ophthalmology. 2016 Mar;123(3):558-70. doi: 10.1016/j.ophtha.2015.10.025. Epub 2015 Nov 19. Ophthalmology. 2016. PMID: 26606867 Free PMC article. Clinical Trial.
Macular Retinal Sublayer Thicknesses in G11778A Leber Hereditary Optic Neuropathy.
Lam BL, Burke SP, Wang MX, Nadayil GA, Rosa PR, Gregori G, Feuer WJ, Cuprill-Nilson S, Vandenbroucke R, Zhang X, Guy J. Lam BL, et al. Among authors: guy j. Ophthalmic Surg Lasers Imaging Retina. 2016 Sep 1;47(9):802-10. doi: 10.3928/23258160-20160901-02. Ophthalmic Surg Lasers Imaging Retina. 2016. PMID: 27631475
971 results