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Inhibiting HER3-mediated tumor cell growth with affibody molecules engineered to low picomolar affinity by position-directed error-prone PCR-like diversification.
Malm M, Kronqvist N, Lindberg H, Gudmundsdotter L, Bass T, Frejd FY, Höidén-Guthenberg I, Varasteh Z, Orlova A, Tolmachev V, Ståhl S, Löfblom J. Malm M, et al. Among authors: hoiden guthenberg i. PLoS One. 2013 May 10;8(5):e62791. doi: 10.1371/journal.pone.0062791. Print 2013. PLoS One. 2013. PMID: 23675426 Free PMC article.
Tumor imaging using a picomolar affinity HER2 binding affibody molecule.
Orlova A, Magnusson M, Eriksson TL, Nilsson M, Larsson B, Höidén-Guthenberg I, Widström C, Carlsson J, Tolmachev V, Ståhl S, Nilsson FY. Orlova A, et al. Cancer Res. 2006 Apr 15;66(8):4339-48. doi: 10.1158/0008-5472.CAN-05-3521. Cancer Res. 2006. PMID: 16618759
Design of an optimized scaffold for affibody molecules.
Feldwisch J, Tolmachev V, Lendel C, Herne N, Sjöberg A, Larsson B, Rosik D, Lindqvist E, Fant G, Höidén-Guthenberg I, Galli J, Jonasson P, Abrahmsén L. Feldwisch J, et al. J Mol Biol. 2010 Apr 30;398(2):232-47. doi: 10.1016/j.jmb.2010.03.002. Epub 2010 Mar 10. J Mol Biol. 2010. PMID: 20226194
22 results